SPYRE THERAPEUTICS, INC. (SYRE) - 13D/13G Filings

Real time Form 13D and 13G transaction reports:

  • Schedule 13D must be filed within ten days after a person or an organization acquires beneficial ownership of more than 5% of a voting class of a company's equity securities.
  • Due to inconsistent filing format, it is highly recommended that you read the orignal filing form.
  • Shares have beem adjusted for stock split.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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Time period
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Reported
DateTime
Transaction
Date
TypeCompany
Symbol
Filed By
Symbol
Shares Owned
% Owned
Shares Vs. Prev ReportView
2026-10-09
5:00 pm
Purchase
2026-10-0713DSPYRE THERAPEUTICS, INC
SYRE
Fairmount Funds Management LLC10,185,961
9.990%
518,760increase
(+5.37%)
Filing
History
2026-10-01
4:05 pm
Purchase
2026-09-2413GSPYRE THERAPEUTICS, INC
SYRE
Paradigm BioCapital Advisors LP4,457,450
5.100%
4,457,450increase
(New Position)
Filing
History
2026-08-14
5:22 pm
Unchanged
2026-06-3013GSPYRE THERAPEUTICS, INC
SYRE
Perceptive Advisors LLC4,319,496
4.900%
0
(Unchanged)
Filing
History
2026-08-14
08:10 am
Purchase
2026-06-3013GSPYRE THERAPEUTICS, INC
SYRE
RTW Investments, LP4,251,996
4.800%
630,000increase
(+17.39%)
Filing
History
2026-06-23
9:45 pm
Purchase
2026-06-2313DSPYRE THERAPEUTICS, INC
SYRE
Fairmount Funds Management LLC9,667,201
9.990%
650,499increase
(+7.21%)
Filing
History
2026-04-22
4:00 pm
Purchase
2026-04-1513GSPYRE THERAPEUTICS, INC
SYRE
Perceptive Advisors LLC4,319,496
5.000%
1,744,773increase
(+67.77%)
Filing
History
2026-04-20
6:00 pm
Purchase
2026-04-1613DSPYRE THERAPEUTICS, INC
SYRE
Fairmount Funds Management LLC9,016,702
9.990%
909,820increase
(+11.22%)
Filing
History
2026-03-27
1:17 pm
Sale
2026-03-1313GSPYRE THERAPEUTICS, INC
SYRE
VANGUARD GROUP INC0
0.000%
-3,066,586decrease
(Position Closed)
Filing
History
2026-02-17
4:15 pm
Sale
2025-12-3113GSPYRE THERAPEUTICS, INC
SYRE
TANG CAPITAL MANAGEMENT, LLC1,892,200
2.400%
-1,307,800decrease
(-40.87%)
Filing
History
2025-10-17
5:00 pm
Purchase
2025-10-1513DSPYRE THERAPEUTICS, INC
SYRE
Fairmount Funds Management LLC8,106,882
9.990%
3,598,303increase
(+79.81%)
Filing
History
2025-07-29
2:40 pm
Purchase
2025-06-3013GSPYRE THERAPEUTICS, INC
SYRE
VANGUARD GROUP INC3,066,586
5.080%
3,066,586increase
(New Position)
Filing
History
2025-07-16
7:02 pm
Purchase
2025-06-3013GSPYRE THERAPEUTICS, INC
SYRE
BlackRock, Inc.
BLK
3,962,635
6.600%
1,299,488increase
(+48.80%)
Filing
History
2025-05-01
4:15 pm
Purchase
2025-04-2413GSPYRE THERAPEUTICS, INC
SYRE
TANG CAPITAL MANAGEMENT, LLC3,200,000
5.300%
3,200,000increase
(New Position)
Filing
History
2025-02-14
6:06 pm
Unchanged
2024-12-3113GSPYRE THERAPEUTICS, INC
SYRE
Venrock Healthcare Capital Partners III, L.P.2,685,448
4.600%
0
(Unchanged)
Filing
History
2025-02-14
4:15 pm
Sale
2024-12-3113GSPYRE THERAPEUTICS, INC
SYRE
Perceptive Advisors LLC2,574,723
4.400%
-297,824decrease
(-10.37%)
Filing
History
2025-02-14
09:00 am
Purchase
2024-12-3113GSPYRE THERAPEUTICS, INC
SYRE
RTW Investments, LP3,621,996
6.200%
1,389,236increase
(+62.22%)
Filing
History
2024-11-14
5:50 pm
Sale
2024-09-3013GSPYRE THERAPEUTICS, INC
SYRE
Venrock Healthcare Capital Partners III, L.P.2,685,448
5.300%
-1,049,066decrease
(-28.09%)
Filing
History
2024-11-14
4:33 pm
Purchase
2024-09-3013GSPYRE THERAPEUTICS, INC
SYRE
Perceptive Advisors LLC2,872,547
5.700%
265,868increase
(+10.20%)
Filing
History
2024-11-14
4:05 pm
Purchase
2024-09-3013GSPYRE THERAPEUTICS, INC
SYRE
Commodore Capital LP1,988,084
3.900%
54,000increase
(+2.79%)
Filing
History
2024-11-14
09:44 am
Sale
2024-09-3013GAEGLEA BIOTHERAPEUTICS, INC. C
AGLE
Deep Track Capital, LP1,000,000
1.970%
-1,184,440decrease
(-54.22%)
Filing
History
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