Real time insider trading transaction history:
- Insiders are prohibited from making short-swing profits by trading their shares within 6 months of the registration or acquiring the shares.
- Shares are not adjusted for stock split.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
What is insider trading>>
- Peter Lynch
What is insider trading>>
Common stock purchase or sale:
| Transaction Date | Reported DateTime | Company | Symbol | Insider Relationship | Shares Traded | Average Price | Total Amount | Shares Owned | Filing |
| 2026-04-01 Sale | 2026-04-03 9:30 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 15,000 | $49.33 | $739,912 | 627,540 (Direct) | View |
| 2026-04-01 Sale | 2026-04-03 9:30 pm | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 7,958 | $50 | $397,900 | 87,542 (Direct) | View |
| 2026-04-01 Sale | 2026-04-03 9:29 pm | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 7,500 | $49.34 | $370,076 | 492,851 (Direct) | View |
| 2026-03-03 Sale | 2026-03-03 9:32 pm | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 2,500 | $40.65 | $101,620 | 500,351 (Direct) | View |
| 2026-03-02 Sale | 2026-03-03 9:31 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 15,000 | $42.19 | $632,866 | 642,540 (Direct) | View |
| 2026-02-02 Sale | 2026-02-04 9:33 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 15,000 | $32.8 | $492,045 | 657,540 (Direct) | View |
| 2026-01-02 Sale | 2026-01-06 9:36 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 15,000 | $30.68 | $460,134 | 671,907 (Direct) | View |
| 2025-12-01 Sale | 2025-12-03 9:52 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 15,000 | $29.02 | $435,356 | 686,907 (Direct) | View |
| 2025-11-03 Sale | 2025-11-05 9:15 pm | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 45,000 | $23.33 | $1,049,778 | 701,907 (Direct) | View |
| 2025-09-02 Sale | 2025-09-03 6:53 pm | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 18,428 | $16.26 | $299,639 | 97,994 (Direct) | View |
| 2024-11-06 Sale | 2024-11-08 4:53 pm | Spyre Therapeutics Inc. | SYRE | Albers Jeffrey W. Director | 6,700 | $36.76 | $246,313 | 27,360 (Indirect) | View |
| 2024-10-25 Sale | 2024-10-28 4:41 pm | Spyre Therapeutics Inc. | SYRE | Albers Jeffrey W. Director | 300 | $36.43 | $10,929 | 34,060 (Indirect) | View |
| 2024-09-03 Sale | 2024-09-05 4:04 pm | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 18,531 | $28.17 | $522,074 | 116,422 (Direct) | View |
Stock options: Exercise, Award, Grant, Conversion
| Transaction Date | Reported DateTime | Exercisable Expiration | Company | Symnbol | Insider Relationship | Shares Traded | Conversion Price | Shares Owned | Filing |
| 2026-04-01 Exercise | 2026-04-03 9:30 pm | N/A 2035-01-15 | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 7,958 | $0 | 87,542 (Direct) | View |
| 2026-04-01 Exercise | 2026-04-03 9:30 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 7,958 | $21.66 | 87,542 (Direct) | View |
| 2026-04-01 Exercise | 2026-04-03 9:29 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 7,500 | $14.5 | 492,851 (Direct) | View |
| 2026-04-01 Exercise | 2026-04-03 9:29 pm | N/A 2033-09-01 | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 7,500 | $0 | 492,851 (Direct) | View |
| 2026-03-03 Exercise | 2026-03-03 9:32 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 2,500 | $14.5 | 500,351 (Direct) | View |
| 2026-03-03 Exercise | 2026-03-03 9:32 pm | N/A 2033-09-01 | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 2,500 | $0 | 500,351 (Direct) | View |
| 2026-01-21 Other | 2026-01-23 9:31 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | HENDERSON MICHAEL THOMAS Director | 63,227 | $0 | 231,833 (Direct) | View |
| 2026-01-09 Option Award | 2026-01-13 9:27 pm | N/A 2036-01-09 | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 140,000 | $0 | 140,000 (Direct) | View |
| 2026-01-09 Option Award | 2026-01-13 9:27 pm | N/A 2036-01-09 | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 528,000 | $0 | 528,000 (Direct) | View |
| 2026-01-09 Option Award | 2026-01-13 9:26 pm | N/A 2036-01-09 | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 140,000 | $0 | 140,000 (Direct) | View |
| 2026-01-09 Option Award | 2026-01-13 9:25 pm | N/A 2036-01-09 | Spyre Therapeutics Inc. | SYRE | King-Jones Heidy See Remarks | 140,000 | $0 | 140,000 (Direct) | View |
| 2025-05-29 Option Award | 2025-06-02 4:39 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | Fairmount Funds Management LLC Harwin Peter Evan Kiselak Tomas Fairmount Healthcare Fund II L.P. Director | 50,000 | $0 | 50,000 (Indirect) | View |
| 2025-05-29 Option Award | 2025-06-02 4:38 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | Stelzer Laurie Director | 25,000 | $0 | 25,000 (Direct) | View |
| 2025-05-29 Option Award | 2025-06-02 4:37 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | Milligan Sandra Director | 25,000 | $0 | 25,000 (Direct) | View |
| 2025-05-29 Option Award | 2025-06-02 4:36 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | McKenna Mark C. Director | 25,000 | $0 | 25,000 (Direct) | View |
| 2025-05-29 Option Award | 2025-06-02 4:35 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | HENDERSON MICHAEL THOMAS Director | 25,000 | $0 | 25,000 (Direct) | View |
| 2025-05-29 Option Award | 2025-06-02 4:34 pm | N/A 2035-05-29 | Spyre Therapeutics Inc. | SYRE | Albers Jeffrey W. Director | 25,000 | $0 | 25,000 (Direct) | View |
| 2025-01-15 Option Award | 2025-01-17 4:36 pm | N/A 2035-01-15 | Spyre Therapeutics Inc. | SYRE | Burrows Scott L Chief Financial Officer | 95,500 | $0 | 95,500 (Direct) | View |
| 2025-01-15 Option Award | 2025-01-17 4:36 pm | N/A 2035-01-15 | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 95,500 | $0 | 95,500 (Direct) | View |
| 2025-01-15 Option Award | 2025-01-17 4:35 pm | N/A 2035-01-15 | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 370,000 | $0 | 370,000 (Direct) | View |
| 2025-01-15 Option Award | 2025-01-17 4:34 pm | N/A 2035-01-15 | Spyre Therapeutics Inc. | SYRE | King-Jones Heidy See Remarks | 95,500 | $0 | 95,500 (Direct) | View |
| 2025-01-10 Other | 2025-01-14 5:16 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | HENDERSON MICHAEL THOMAS Director | 105,379 | $0 | 210,758 (Direct) | View |
| 2024-10-01 Option Award | 2024-10-01 6:34 pm | N/A 2034-10-01 | Spyre Therapeutics Inc. | SYRE | Sloan Sheldon Chief Medical Officer | 400,000 | $0 | 400,000 (Direct) | View |
| 2024-05-14 Option Award | 2024-05-16 4:10 pm | N/A 2034-05-14 | Spyre Therapeutics Inc. | SYRE | Fairmount Funds Management LLC Kiselak Tomas Harwin Peter Evan Director | 22,646 | $0 | 22,646 (Indirect) | View |
| 2024-05-14 Option Award | 2024-05-16 4:10 pm | N/A 2034-05-14 | Spyre Therapeutics Inc. | SYRE | Milligan Sandra Director | 21,980 | $0 | 21,980 (Direct) | View |
| 2024-05-14 Option Award | 2024-05-16 4:10 pm | N/A 2034-05-14 | Spyre Therapeutics Inc. | SYRE | Albers Jeffrey W. Director | 11,323 | $0 | 11,323 (Direct) | View |
| 2024-05-14 Option Award | 2024-05-16 4:10 pm | N/A 2034-05-14 | Spyre Therapeutics Inc. | SYRE | Stelzer Laurie Director | 11,323 | $0 | 11,323 (Direct) | View |
| 2024-05-14 Option Award | 2024-05-16 4:10 pm | N/A 2034-05-14 | Spyre Therapeutics Inc. | SYRE | HENDERSON MICHAEL THOMAS Director | 11,323 | $0 | 11,323 (Direct) | View |
| 2024-04-25 Exercise | 2024-04-25 4:55 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | Fairmount Funds Management LLC Fairmount Healthcare Fund II L.P. Kiselak Tomas Harwin Peter Evan Director | 3,730,672 | $0 | 5,176,222 (Indirect) | View |
| 2024-02-15 Option Award | 2024-02-20 9:21 pm | N/A N/A | Spyre Therapeutics Inc. | SYRE | Turtle Cameron Chief Executive Officer | 400 | $9.82 | 746,907 (Direct) | View |
| 2024-02-01 Option Award | 2024-02-05 5:29 pm | N/A 2034-02-01 | Spyre Therapeutics Inc. | SYRE | McKenna Mark C. Director | 40,000 | $0 | 40,000 (Direct) | View |