| 1 | RA CAPITAL MANAGEMENT L.P.
RA Capital Healthcare Fund LP
RA Capital Nexus Fund II L.P.
Kolchinsky Peter
Shah Rajeev M.
Director
10% Owner | 2025-11-06 16:29:43 | 6,681,307
0 | 6,681,307 | Form 13D |
| 2 | GADICKE ANSBERT
MPM ONCOLOGY INNOVATIONS FUND LP
UBS Oncology Impact Fund L.P.
Oncology Impact Fund (Cayman) Management L.P.
MPM Oncology Impact Management LP
MPM Oncology Innovations Fund GP LLC
MPM Oncology Impact Management GP LLC
10% Owner | 2021-05-06 16:19:54 | 0
6,672,183 | 6,672,183 | Form 4 |
| 3 | Asanuma Sakae
Director
10% Owner | 2021-05-04 16:31:20 | 0
5,866,830 | 5,866,830 | Form 4 |
| 4 | GADICKE ANSBERT
MPM ONCOLOGY INNOVATIONS FUND LP
UBS Oncology Impact Fund L.P.
Oncology Impact Fund (Cayman) Management L.P.
MPM BioImpact LLC
MPM Oncology Innovations Fund GP LLC
MPM ASSET MANAGEMENT LLC
Former 10% Owner | 2025-12-04 18:18:45 | 0
4,784,111 | 4,784,111 | Form 4 |
| 5 | MPM BioVentures 2014 L.P.
MPM BioVentures 2014 (B) L.P.
MPM BioVentures 2014 LLC
MPM BioVentures 2014 GP LLC
MPM Asset Management Investors BV2014 LLC
Former 10% Owner | 2026-01-16 17:36:28 | 3,368,670
0 | 3,368,670 | Form 13D |
| 6 | MPM BioVentures 2014 L.P.
MPM BioVentures 2014 (B) L.P.
MPM BioVentures 2014 LLC
MPM BioVentures 2014 GP LLC
MPM Asset Management Investors BV2014 LLC
Foley Todd
10% Owner | 2026-01-16 17:36:28 | 3,368,670
0 | 3,368,670 | Form 13D |
| 7 | EVNIN LUKE
Director | 2026-01-15 17:22:58 | 0
2,198,642 | 2,198,642 | Form 4 |
| 8 | Taiho Ventures LLC
10% Owner | 2021-05-13 16:30:34 | 2,068,909
0 | 2,068,909 | Form 13D |
| 9 | Arkin Bio Ventures 2 L.P.
Arkin Bio Ventures GPGP Ltd.
Arkin Moshe
10% Owner | 2021-05-10 11:21:05 | 2,046,634
0 | 2,046,634 | Form 13D |
| 10 | Longwood Fund III GP LLC
Longwood Fund III L.P.
10% Owner | 2021-05-14 16:42:01 | 1,677,082
0 | 1,677,082 | Form 13G |
| 11 | UPMC
10% Owner | 2021-05-04 16:30:22 | 1,097,756
0 | 1,097,756 | Form 4 |
| 12 | Flynn James E
Deerfield Mgmt L.P.
DEERFIELD MANAGEMENT COMPANY L.P. (SERIES C)
DEERFIELD PARTNERS L.P.
Possible Member of 10% Group
10% Owner | 2022-02-11 16:11:11 | 958,125
0 | 958,125 | Form 13G |
| 13 | Sphera Global Healthcare Management LP
Sphera Global Healthcare GP Ltd.
SPHERA FUNDS MANAGEMENT LTD.
10% Owner | 2021-05-04 13:21:04 | 0
787,997 | 787,997 | Form 4 |
| 14 | HICKLIN DANIEL J
See Remarks | 2025-01-06 17:41:13 | 778,342
0 | 778,342 | Form 4 |
| 15 | HBM Healthcare Investments (Cayman) Ltd.
10% Owner | 2021-05-05 16:00:36 | 625,995
0 | 625,995 | Form 4 |
| 16 | Karunatilake Chulani
Chief Technology Officer | 2025-01-06 17:43:56 | 303,129
0 | 303,129 | Form 4 |
| 17 | Isaacs Randi
Chief Medical Officer | 2025-01-06 17:44:09 | 255,651
0 | 255,651 | Form 4 |
| 18 | Trost Timothy W.
Chief Financial Officer | 2025-01-06 17:44:52 | 210,358
0 | 210,358 | Form 4 |
| 19 | Bloom Steven H.
Chief Business Officer | 2025-05-02 17:38:59 | 201,720
0 | 201,720 | Form 4 |
| 20 | Seidel-Dugan Cynthia
Chief Scientific Officer | 2024-01-04 16:30:10 | 150,000
0 | 150,000 | Form 4 |
| 21 | Lubman Ellen
Chief Business Officer | 2025-01-06 17:51:18 | 131,900
0 | 131,900 | Form 4 |
| 22 | Leonard Reid
Chief Operating Officer | 2023-01-09 21:34:46 | 93,600
0 | 93,600 | Form 4 |
| 23 | Atkins Michael B.
Director | 2025-06-13 16:10:04 | 27,000
0 | 27,000 | Form 4 |
| 24 | Sherman Michael A.
Director | 2025-06-13 16:10:06 | 27,000
0 | 27,000 | Form 4 |
| 25 | Chatterjee Meeta
Director | 2025-06-13 16:10:10 | 27,000
0 | 27,000 | Form 4 |
| 26 | Morrison Briggs
Director | 2025-06-13 16:10:15 | 27,000
0 | 27,000 | Form 4 |
| 27 | Lazarus Alon
Director | 2025-06-13 16:10:16 | 27,000
0 | 27,000 | Form 4 |
| 28 | DiRocco Derek
Director | 2024-05-24 19:52:50 | 17,500
0 | 17,500 | Form 4 |
| 29 | Singhal Anil K.
Director | 2025-06-13 16:10:05 | 17,358
0 | 17,358 | Form 4 |