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Insider Trading - Lyra Therapeutics Inc. (LYRA)

"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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LYRA Insider Trading Transactions for Lyra Therapeutics Inc.

Common stock purchase or sale:

Transaction Date	Reported DateTime	Company	Symbol	Insider Relationship	Shares Traded	Average Price	Total Amount	Shares Owned	Filing
2020-05-05 Purchase	2020-05-06 7:30 pm	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	62,500	$16	$1,000,000	7,274 (Indirect)	View
2020-05-05 Sale	2020-05-06 7:30 pm	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	9,674	$16	$154,784	7,274 (Indirect)	View
2020-05-05 Purchase	2020-05-06 7:32 pm	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	250,000	$16	$4,000,000	553,123 (Indirect)	View
2020-05-05 Sale	2020-05-06 7:32 pm	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	24,183	$16	$386,928	553,123 (Indirect)	View
2020-05-05 Purchase	2020-05-06 7:38 pm	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	250,000	$16	$4,000,000	553,123 (Indirect)	View
2020-05-05 Sale	2020-05-06 7:38 pm	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	24,183	$16	$386,928	553,123 (Indirect)	View
2020-05-05 Purchase	2020-05-15 6:16 pm	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	155,000	$16	$2,480,000	155,000 (Indirect)	View
2020-05-05 Sale	2020-05-15 6:16 pm	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	16,909	$16	$270,544	155,000 (Indirect)	View
2020-05-05 Purchase	2020-05-29 5:34 pm	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	625,000	$16	$10,000,000	1,934,115 (Indirect)	View
2020-12-16 Purchase	2020-12-17 4:05 pm	Lyra Therapeutics Inc.	LYRA	snyderman nancy lynn MD Director	1,025	$9.72	$9,963	1,025 (Direct)	View

Stock options: Exercise, Award, Grant, Conversion

Transaction Date	Reported DateTime	Exercisable Expiration	Company	Symnbol	Insider Relationship	Shares Traded	Conversion Price	Shares Owned	Filing
2020-04-30 Option Award	2020-05-01 6:31 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	Noyes Corinne See Remarks	9,782	$0	9,782 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:31 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	Edgerly-Pflug Laura See Remarks	20,046	$0	20,046 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:31 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	14,500	$0	14,500 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:34 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	Elsey R Don CFO	20,635	$0	20,635 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:35 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	19,661	$16	48,660 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:35 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	14,500	$0	14,500 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:36 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	LANGER ROBERT Director	14,500	$0	14,500 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:36 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	Palasis Maria CEO	326,303	$0	326,303 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:38 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	Poukalov Konstantin Director	14,500	$0	14,500 (Direct)	View
2020-04-30 Option Award	2020-05-01 6:44 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	ALTMAN MICHAEL SETH Director	14,500	$0	14,500 (Direct)	View
2020-04-30 Option Award	2020-05-01 9:06 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC EDELMAN JOSEPH Director 10% Owner	14,500	$0	14,500 (Indirect)	View
2020-04-30 Option Award	2020-05-01 9:06 pm	N/A 2030-04-29	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC EDELMAN JOSEPH Director 10% Owner	14,500	$0	14,500 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	993,981	$0	993,981 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	19,370	$0	19,370 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	9,936	$0	9,936 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	6,807	$0	6,807 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	17,304	$8.63	1,011,285 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	337	$8.63	19,707 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	173	$8.63	10,109 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	118	$8.63	6,925 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	6,268,687	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	122,177	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	62,687	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	42,941	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	3,296,014	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	64,237	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	32,961	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	22,580	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	8,610,081	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	167,809	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	86,101	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	58,980	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	7,693,406	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	149,944	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	76,934	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	52,700	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	6,418,387	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	125,094	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	64,183	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	43,966	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	1,988,991	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	38,765	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	19,890	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:30 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	13,625	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	2020-01-10 2030-01-10	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	17,304	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	2020-01-10 2030-01-10	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	337	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	2020-01-10 2030-01-10	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	173	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:30 pm	2020-01-10 2030-01-10	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co. V L.L.C. Polaris Venture Partners Special Founders' Fund V L.P. Polaris Venture Partners V L.P. Polaris Venture Partners Entrepreneurs' Fund V L.P. Polaris Venture Partners Founders' Fund V L.P. MCGUIRE TERRANCE Flint Jonathan A 10% Owner	118	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:31 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	LANGER ROBERT Director	668	$0	15,167 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:31 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	LANGER ROBERT Director	23,057	$0	0 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	651,453	$0	651,453 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	319,303	$0	319,303 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	471,929	$0	471,929 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	21,060	$8.63	672,513 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	10,322	$8.63	329,625 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	13,449	$8.63	485,378 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,157,670	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	567,420	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,725,090	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,105,754	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	541,973	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,647,727	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	3,051,758	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,495,786	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,948,948	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	3,270,702	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,603,102	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	2,088,772	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	4,587,608	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	2,248,569	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	2,929,790	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	3,745,346	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,835,743	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	2,391,895	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	3,124,633	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,531,507	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,995,489	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	2,420,729	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,186,496	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:32 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	1,545,953	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	21,060	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	10,322	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:32 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	ANDERSON EDWARD T Director 10% Owner	13,449	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Roberts Carmichael 10% Owner	415	$0	58,414 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Roberts Carmichael 10% Owner	14,318	$0	0 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	316,980	$0	316,980 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	5,940	$0	5,940 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	3,386,690	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	63,490	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	3,234,812	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	60,642	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	3,481,517	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	65,267	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	827,483	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Polaris Venture Management Co IV LLC POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP POLARIS VENTURE PARTNERS IV LP 10% Owner	15,513	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	6,404	$0	55,064 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	97,216	$0	0 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	55,991	$0	0 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:34 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	WHITESIDES GEORGE M Director	67,672	$0	0 (Direct)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	651,453	$0	651,453 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	319,303	$0	319,303 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	471,929	$0	471,929 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	21,060	$8.63	672,513 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	10,322	$8.63	329,625 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	13,449	$8.63	485,378 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,157,670	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	567,420	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,725,090	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,105,754	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	541,973	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,647,727	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	3,051,758	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,495,786	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,948,948	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	3,270,702	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,603,102	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	2,088,772	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	4,587,608	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	2,248,569	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	2,929,790	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	3,745,346	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,835,743	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	2,391,895	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	3,124,633	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,531,507	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,995,489	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	2,420,729	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,186,496	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 7:38 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	1,545,953	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	21,060	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	10,322	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 7:38 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	NBVM GP LLC DAMORE RICHARD A NORTH BRIDGE VENTURE PARTNERS V A LP NORTH BRIDGE VENTURE PARTNERS V-B LP North Bridge Venture Partners VI L P North Bridge Venture Management V L.P. North Bridge Venture Management VI L.P. 10% Owner	13,449	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	773,327	$0	773,327 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	1,132,016	$0	1,132,016 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	470,739	$0	1,244,066 (Indirect)	View
2020-05-05 Exercise	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	141,221	$8.63	1,385,287 (Indirect)	View
2020-05-05 Tax Withholding	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	76,172	$16	1,309,115 (Indirect)	View
2020-05-05 Exercise	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	339,604	$8.63	1,471,620 (Indirect)	View
2020-05-05 Tax Withholding	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	183,174	$16	1,288,446 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	26,666,666	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	39,035,324	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-06 9:10 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	16,232,511	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 9:10 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	141,221	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-06 9:10 pm	2020-01-17 2030-01-10	Lyra Therapeutics Inc.	LYRA	PERCEPTIVE ADVISORS LLC PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Perceptive LS (A) LLC EDELMAN JOSEPH Director 10% Owner	339,604	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-15 6:16 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	338,330	$0	338,330 (Indirect)	View
2020-05-05 Conversion	2020-05-15 6:16 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	104,608	$0	442,948 (Indirect)	View
2020-05-05 Exercise	2020-05-15 6:16 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	31,382	$8.63	474,330 (Indirect)	View
2020-05-05 Conversion	2020-05-15 6:16 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	11,666,666	$0	0 (Indirect)	View
2020-05-05 Conversion	2020-05-15 6:16 pm	N/A N/A	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	3,607,224	$0	0 (Indirect)	View
2020-05-05 Exercise	2020-05-15 6:16 pm	2020-01-27 2030-01-27	Lyra Therapeutics Inc.	LYRA	Soleus Private Equity GP I LLC Soleus Private Equity Fund I L.P. Soleus PE GP I LLC Soleus Capital Master Fund L.P. Soleus Capital LLC Soleus Capital Group LLC Levy Guy 10% Owner	31,382	$0	0 (Indirect)	View
2020-06-24 Option Award	2020-06-26 4:18 pm	N/A 2030-06-24	Lyra Therapeutics Inc.	LYRA	Richard Robert E. VP	35,000	$0	35,000 (Direct)	View
2020-08-03 Option Award	2020-08-05 4:06 pm	N/A 2030-08-03	Lyra Therapeutics Inc.	LYRA	Nelson Pamela E. VP	35,000	$0	35,000 (Direct)	View
2020-10-27 Option Award	2020-10-29 8:45 pm	N/A 2030-10-26	Lyra Therapeutics Inc.	LYRA	snyderman nancy lynn MD Director	14,500	$0	14,500 (Direct)	View
2021-02-08 Option Award	2021-02-10 4:05 pm	N/A 2031-02-07	Lyra Therapeutics Inc.	LYRA	Richard Robert E. VP	18,000	$0	18,000 (Direct)	View
2021-02-08 Option Award	2021-02-10 4:05 pm	N/A 2031-02-07	Lyra Therapeutics Inc.	LYRA	Nelson Pamela E. VP	13,000	$0	13,000 (Direct)	View
2021-02-08 Option Award	2021-02-10 4:05 pm	N/A 2031-02-07	Lyra Therapeutics Inc.	LYRA	Noyes Corinne See Remarks	30,000	$0	30,000 (Direct)	View
2021-02-08 Option Award	2021-02-10 4:05 pm	N/A 2031-02-07	Lyra Therapeutics Inc.	LYRA	Palasis Maria CEO	120,000	$0	120,000 (Direct)	View
2021-02-08 Option Award	2021-02-10 4:05 pm	N/A 2031-02-07	Lyra Therapeutics Inc.	LYRA	Elsey R Don CFO	45,000	$0	45,000 (Direct)	View