List of insiders holdings for IONIS PHARMACEUTICALS INC:
- Shares directly owned by the insider.
- Shares indirectly owned by the insider.
- Total shares owned by the insider (sum of shares directly and indirectly owned).
- Total market value if available.
- Shares are not adjusted for stock split.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
What is insider trading>>
- Peter Lynch
What is insider trading>>
| # | Insider Holder Name | Report Date Time | Shares Owned Directly Indirectly | Total Shares Owned | Filing |
| 1 | LILLY ELI & CO 10% Owner | 2006-02-06 16:40:31 | 2,500,000 0 | 2,500,000 | Form 13G |
| 2 | CROOKE STANLEY T Exec Chairman of the Board | 2021-01-28 19:22:03 | 2,021 497,502 | 499,523 | Form 4 |
| 3 | BERTHELSEN SPENCER R Director | 2025-07-17 16:53:48 | 161,233 70 | 161,303 | Form 4 |
| 4 | Geary Richard S EVP, Chief Development Officer | 2025-11-07 17:12:44 | 92,695 0 | 92,695 | Form 4 |
| 5 | Monia Brett P Chief Executive Officer | 2026-01-06 17:35:06 | 85,410 0 | 85,410 | Form 4 |
| 6 | JONAS JEFFREY M Executive Vice President | 2008-01-04 21:27:46 | 78,936 0 | 78,936 | Form 4 |
| 7 | MUTO FREDERICK T Director | 2022-07-19 19:21:23 | 76,482 1,500 | 77,982 | Form 4 |
| 8 | Swayze Eric EVP Research | 2026-01-06 17:35:26 | 76,271 406 | 76,677 | Form 4 |
| 9 | Hayden Michael R Director | 2025-07-17 16:54:01 | 64,195 2,000 | 66,195 | Form 4 |
| 10 | PARSHALL B LYNNE Director | 2025-10-16 20:16:14 | 61,344 0 | 61,344 | Form 4 |
| 11 | XANTHOPOULOS KLEANTHIS G President of Regulus | 2007-12-05 17:42:55 | 60,000 0 | 60,000 | Form 4 |
| 12 | Devers Shannon L. EVP, Chief Human Resources Ofc | 2026-01-09 17:08:28 | 58,199 0 | 58,199 | Form 4 |
| 13 | WENDER JOSEPH H Director | 2025-12-03 19:01:07 | 16,000 36,035 | 52,035 | Form 4 |
| 14 | HERMAN JOAN E Director | 2025-11-20 17:12:11 | 46,086 0 | 46,086 | Form 4 |
| 15 | Castleman Breaux Director | 2020-07-06 17:30:53 | 44,291 0 | 44,291 | Form 4 |
| 16 | Wedel Mark K VP & Chief Medical Officer | 2007-07-10 18:21:04 | 42,410 0 | 42,410 | Form 4 |
| 17 | ECKER DAVID J Vice President | 2008-09-03 17:57:37 | 12,640 28,713 | 41,353 | Form 4 |
| 18 | LOSCALZO JOSEPH Director | 2025-11-03 20:14:50 | 36,330 0 | 36,330 | Form 4 |
| 19 | Cadoret-Manier Onaiza EVP,Chf GL Pdt Str & Oper Ofc | 2024-09-04 20:42:24 | 35,788 0 | 35,788 | Form 4/A |
| 20 | Treble Michael J Vice President, Pres of Ibis | 2008-08-13 18:49:13 | 32,500 0 | 32,500 | Form 4 |
| 21 | Boyce Sarah Chief Business Officer | 2018-01-17 21:23:57 | 32,274 0 | 32,274 | Form 4 |
| 22 | COLE DOUGLAS L Vice President | 2004-03-09 18:06:38 | 31,616 0 | 31,616 | Form 4 |
| 23 | KLEIN JOSEPH III Director | 2025-11-28 17:51:58 | 16,346 12,100 | 28,446 | Form 4 |
| 24 | HOUGEN ELIZABETH L EVP, Finance & CFO | 2026-01-06 17:34:40 | 25,770 0 | 25,770 | Form 4 |
| 25 | LEVIN ARTHUR A Vice President | 2007-04-27 19:44:18 | 25,377 0 | 25,377 | Form 4 |
| 26 | Reikes Peter N Director | 2021-10-19 18:29:26 | 24,886 0 | 24,886 | Form 4 |
| 27 | Baroldi Joseph EVP, Chief Business Officer | 2026-01-06 17:34:07 | 19,350 2,600 | 21,950 | Form 4 |
| 28 | O'NEIL PATRICK R. EVP CLO & General Counsel | 2026-01-06 17:35:13 | 19,350 0 | 19,350 | Form 4 |
| 29 | Schneider Eugene EVP, Chf Clinical Develop Ofcr | 2026-01-06 17:35:20 | 19,350 0 | 19,350 | Form 4 |
| 30 | Jenne Kyle EVP, Chf GL Pdt Str Ofcr | 2026-01-06 17:36:44 | 19,350 0 | 19,350 | Form 4 |
| 31 | Birchler Brian EVP, Corp and Development Ops | 2026-01-06 17:34:24 | 19,350 0 | 19,350 | Form 4 |
| 32 | BENNETT C FRANK EVP, Chief Scientific Officer | 2026-01-06 17:34:16 | 19,350 0 | 19,350 | Form 4 |
| 33 | Diaz Allene M. Director | 2025-08-26 17:23:52 | 18,368 0 | 18,368 | Form 4 |
| 34 | MCNEIL JOHN A Vice President | 2005-01-04 17:57:59 | 18,158 0 | 18,158 | Form 4 |
| 35 | LOWENSTAM PATRICIA Vice President | 2005-01-04 17:52:22 | 18,158 0 | 18,158 | Form 4 |
| 36 | YANG MICHAEL J. Director | 2025-07-17 16:54:38 | 15,090 0 | 15,090 | Form 4 |
| 37 | DiMarchi Richard D Director | 2010-07-02 14:29:11 | 15,000 0 | 15,000 | Form 4 |
| 38 | LUNDSTEDT KAREN S Vice President | 2004-03-12 17:59:32 | 14,407 0 | 14,407 | Form 4 |
| 39 | McDevitt Damien Chief Business Officer | 2019-07-17 17:39:11 | 13,198 0 | 13,198 | Form 4 |
| 40 | SKALETSKY MARK B Director | 2004-07-02 17:18:51 | 10,000 0 | 10,000 | Form 4 |
| 41 | GABRIELI CHRISTOPHER Director | 2005-07-06 18:46:25 | 10,000 0 | 10,000 | Form 4 |
| 42 | Kordasiewicz Holly B. EVP, Chief Development Officer | 2026-01-06 17:34:59 | 9,100 0 | 9,100 | Form 4 |
| 43 | HOLMLUND JON T Vice President | 2004-02-11 18:47:09 | 1,966 5,593 | 7,559 | Form 4/A |
| 44 | BROWN RICHARD K Vice President | 2006-03-09 18:32:02 | 5,118 0 | 5,118 | Form 4 |
| 45 | REED JOHN C Director | 2012-09-06 21:39:45 | 4,900 0 | 4,900 | Form 4 |
| 46 | STEIN ARON Vice President | 2004-07-02 17:25:54 | 2,136 0 | 2,136 | Form 4 |
| 47 | DE HAAN HANS A VP, Drug Development | 2004-05-05 16:07:37 | 0 0 | 0 | Form 4 |