Upstream Bio, Inc. (UPB) - Insider Holders & Insider Ownership

List of insiders holdings for Upstream Bio, Inc.:

Shares directly owned by the insider.
Shares indirectly owned by the insider.
Total shares owned by the insider (sum of shares directly and indirectly owned).
Total market value if available.
Shares are not adjusted for stock split.

"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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#	Insider Holder Name	Report Date Time	Shares Owned Directly Indirectly	Total Shares Owned	Filing
1	AI Upstream LLC AI Biotechnology LLC Access Industries Holdings LLC ACCESS INDUSTRIES MANAGEMENT LLC Blavatnik Len 10% Owner	2024-10-22 16:06:27	5,494,410 0	5,494,410	Form 13D
2	ORBIMED ADVISORS LLC OrbiMed Capital GP VIII LLC OrbiMed Advisors Israel II Ltd OrbiMed Israel GP II L.P. Director 10% Owner	2024-10-17 16:17:52	0 4,554,873	4,554,873	Form 4
3	Wellington Biomedical Innovation Master Investors (Cayman) II L.P. 10% Owner	2024-10-15 19:21:47	894,733 0	894,733	Form 4
4	Sutherland Everett Rand Chief Executive Officer	2026-09-17 16:05:05	68,717 0	68,717	Form 4
5	Deykin Aaron Chief Medical Officer	2026-09-17 16:05:14	32,302 0	32,302	Form 4
6	GRAY MICHAEL CFO and COO	2026-09-17 16:05:26	27,942 0	27,942	Form 4
7	Houghton Adam Chief Business Officer	2026-09-17 16:05:03	22,901 0	22,901	Form 4
8	Chimovits Erez Director	2026-06-11 20:00:03	17,096 0	17,096	Form 4
9	Ratcliffe Liam Director	2026-06-11 20:00:05	17,096 0	17,096	Form 4
10	Beckman Daniella Director	2026-06-11 20:00:06	17,096 0	17,096	Form 4
11	Fleming Harold Edward Director	2026-06-11 20:00:08	17,096 0	17,096	Form 4
12	Renaud Ronald C JR Director	2026-06-11 20:00:09	17,096 0	17,096	Form 4
13	Ruddy Marcella K. Director	2026-06-11 20:00:10	17,096 0	17,096	Form 4
14	Ambrose Allison General Counsel	2026-09-17 16:05:21	15,563 0	15,563	Form 4