| 1 | EcoR1 Capital LLC 10% Owner | 2025-05-16 19:22:17 | 10,688,978 0 | 10,688,978 | Form 13D |
| 2 | GADICKE ANSBERT UBS Oncology Impact Fund L.P. MPM Oncology Impact Management LP Oncology Impact Fund (Cayman) Management L.P. MPM Oncology Impact Management GP LLC 10% Owner | 2021-04-13 16:15:02 | 0 6,004,368 | 6,004,368 | Form 4 |
| 3 | GADICKE ANSBERT MPM BioImpact LLC Oncology Impact Fund (Cayman) Management L.P. UBS Oncology Impact Fund L.P. Former 10% Owner | 2025-05-15 17:34:15 | 0 3,452,797 | 3,452,797 | Form 4 |
| 4 | RA CAPITAL MANAGEMENT L.P. RA Capital Healthcare Fund LP Kolchinsky Peter Shah Rajeev M. Former 10% Owner | 2025-05-19 17:46:06 | 2,134,806 0 | 2,134,806 | Form 13D |
| 5 | MPM BIOVENTURES 2018 L.P. MPM BioVentures 2018 LLC MPM BioVentures 2018 GP LLC Former 10% Owner | 2025-05-15 17:33:28 | 0 2,108,594 | 2,108,594 | Form 4 |
| 6 | MPM BioVentures 2014 L.P. MPM BioVentures 2014 (B) L.P. MPM Asset Management Investors BV2014 LLC MPM BioVentures 2014 GP LLC MPM BioVentures 2014 LLC MPM BIOVENTURES 2018 (B) L.P. MPM ASSET MANAGEMENT INVESTORS BV2018 LLC EVNIN LUKE Foley Todd Former 10% Owner | 2025-05-15 17:32:22 | 0 2,108,594 | 2,108,594 | Form 4 |
| 7 | Lager Joanne Jenkins Chief Medical Officer | 2023-03-10 19:53:52 | 130,000 0 | 130,000 | Form 4 |
| 8 | Iannone Robert Director | 2024-06-13 20:00:03 | 24,200 0 | 24,200 | Form 4 |
| 9 | DeSimone Jill Director | 2024-06-13 20:00:06 | 24,200 0 | 24,200 | Form 4 |
| 10 | Davis Aaron I. Director | 2024-06-13 20:00:09 | 24,200 0 | 24,200 | Form 4 |
| 11 | Ho Tony W Director | 2024-06-13 20:00:13 | 24,200 0 | 24,200 | Form 4 |
| 12 | DiRocco Derek Director | 2023-06-15 19:53:23 | 22,383 0 | 22,383 | Form 4 |
| 13 | Van Hauwermeiren Timothy Director | 2025-05-14 20:00:06 | 22,346 0 | 22,346 | Form 4 |
| 14 | RODEN MATTHEW Director | 2022-06-10 19:56:03 | 17,538 0 | 17,538 | Form 4 |
| 15 | Biniszkiewicz Detlev Director | 2022-06-10 19:46:11 | 17,538 0 | 17,538 | Form 4 |
| 16 | Belawat Priyanka Director | 2020-07-23 19:27:24 | 0 0 | 0 | Form 3 |
| 17 | Boxer Capital LLC Boxer Asset Management Inc. LEWIS JOSEPH Davis Aaron I. See remarks | 2024-10-15 19:20:12 | 0 0 | 0 | Form 13D |
| 18 | Boxer Capital LLC Boxer Asset Management Inc. LEWIS JOSEPH MVA Investors LLC Davis Aaron I. Director 10% Owner | 2024-10-15 19:20:12 | 0 0 | 0 | Form 13D |
| 19 | Hallal David Director | 2025-08-29 16:30:04 | 0 0 | 0 | Form 4 |
| 20 | RHOADS ANN D Director | 2025-08-29 16:30:06 | 0 0 | 0 | Form 4 |
| 21 | McGrath Yvonne Chief Scientific Officer | 2025-08-29 16:30:11 | 0 0 | 0 | Form 4 |
| 22 | Gall Matthew Chief Financial Officer | 2025-08-29 16:30:13 | 0 0 | 0 | Form 4 |
| 23 | Feltquate David Chief Medical Officer | 2025-08-29 16:30:24 | 0 0 | 0 | Form 4 |
| 24 | Lee David K Director | 2025-08-29 16:30:26 | 0 0 | 0 | Form 4 |
| 25 | Detheux Michel Chief Executive Officer | 2025-08-29 16:30:29 | 0 0 | 0 | Form 4 |
| 26 | Call Matthew Chief Operating Officer | 2025-08-29 16:30:31 | 0 0 | 0 | Form 4 |