Opaleye Management Inc. - 13D/13G Filings

Real time Form 13D and 13G transaction reports:

  • Schedule 13D must be filed within ten days after a person or an organization acquires beneficial ownership of more than 5% of a voting class of a company's equity securities.
  • Due to inconsistent filing format, it is highly recommended that you read the orignal filing form.
  • Shares have beem adjusted for stock split.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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Time period
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Reported
DateTime
Transaction
Date
TypeCompany
Symbol
Filed By
Symbol
Shares Owned
% Owned
Shares Vs. Prev ReportView
2026-06-29
4:05 pm
Purchase
2026-06-2613GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,895,107
13.300%
274,738increase
(+10.48%)
Filing
History
2026-05-22
4:05 pm
Purchase
2026-05-2113GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,620,369
12.030%
58,419increase
(+2.28%)
Filing
History
2026-05-11
4:25 pm
Purchase
2026-03-3113GREZOLUTE INC
RZLT
Opaleye Management Inc.6,300,000
6.580%
1,387,100increase
(+28.23%)
Filing
History
2026-05-11
4:23 pm
Sale
2026-03-3113GKARYOPHARM THERAPEUTICS INC CO
KPTI
Opaleye Management Inc.619,089
2.670%
-949,913decrease
(-60.54%)
Filing
History
2026-05-11
4:20 pm
Sale
2026-03-3113GHARROW INC
HROW
Opaleye Management Inc.2,832,230
7.610%
-987,770decrease
(-25.86%)
Filing
History
2026-05-11
4:17 pm
Purchase
2026-03-3113GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,561,950
11.770%
173,312increase
(+7.26%)
Filing
History
2026-05-06
4:05 pm
Purchase
2026-03-3113GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.500,000
15.410%
39,665increase
(+8.62%)
Filing
History
2026-05-06
4:05 pm
Unchanged
2026-03-3113GQ32 BIO INC
QTTB
Opaleye Management Inc.1,256,228
8.590%
0
(Unchanged)
Filing
History
2026-05-05
4:05 pm
Sale
2026-03-3113GCODEXIS INC
CDXS
Opaleye Management Inc.6,785,000
7.470%
-4,738decrease
(-0.07%)
Filing
History
2026-05-04
4:05 pm
Sale
2026-05-0113GSANUWAVE HEALTH INC PAR $0
SNWV
Opaleye Management Inc.858,569
9.990%
-85,563decrease
(-9.06%)
Filing
History
2026-04-08
8:25 pm
Purchase
2026-04-0113GPASITHEA THERAPEUTICS CORP COM
KTTA
Opaleye Management Inc.2,491,000
9.990%
2,491,000increase
(New Position)
Filing
History
2026-03-23
6:52 pm
Purchase
2026-02-1313GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.460,335
16.520%
92,968increase
(+25.31%)
Filing
History
2026-03-04
4:05 pm
Purchase
2026-03-0213GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,388,638
11.000%
195,049increase
(+8.89%)
Filing
History
2026-02-20
8:22 pm
Sale
2026-02-1913GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,193,589
10.090%
-75,000decrease
(-3.31%)
Filing
History
2026-02-20
8:13 pm
Purchase
2026-02-1913GQ32 BIO INC
QTTB
Opaleye Management Inc.1,256,228
8.650%
1,256,228increase
(New Position)
Filing
History
2026-02-20
4:10 pm
Purchase
2026-02-1913GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,268,589
10.430%
197,805increase
(+9.55%)
Filing
History
2026-02-06
4:05 pm
Purchase
2025-12-3113GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,070,784
9.520%
195,642increase
(+10.43%)
Filing
History
2026-01-23
4:05 pm
Sale
2025-12-3113GCODEXIS INC
CDXS
Opaleye Management Inc.6,789,738
7.520%
-2,198,251decrease
(-24.46%)
Filing
History
2025-12-19
4:05 pm
Purchase
2025-12-1213GREZOLUTE INC
RZLT
Opaleye Management Inc.4,912,900
5.300%
4,912,900increase
(New Position)
Filing
History
2025-12-05
4:05 pm
Purchase
2025-12-0313GCODEXIS INC
CDXS
Opaleye Management Inc.8,987,989
9.950%
1,463,989increase
(+19.46%)
Filing
History
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