Opaleye Management Inc. - 13D/13G Filings

Real time Form 13D and 13G transaction reports:

  • Schedule 13D must be filed within ten days after a person or an organization acquires beneficial ownership of more than 5% of a voting class of a company's equity securities.
  • Due to inconsistent filing format, it is highly recommended that you read the orignal filing form.
  • Shares have beem adjusted for stock split.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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Reported
DateTime
Transaction
Date
TypeCompany
Symbol
Filed By
Symbol
Shares Owned
% Owned
Shares Vs. Prev ReportView
2026-04-08
8:25 pm
Purchase
2026-04-0113GPASITHEA THERAPEUTICS CORP COM
KTTA
Opaleye Management Inc.2,491,000
9.990%
2,491,000increase
(New Position)
Filing
History
2026-03-23
6:52 pm
Purchase
2026-02-1313GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.460,335
16.520%
92,968increase
(+25.31%)
Filing
History
2026-03-04
4:05 pm
Purchase
2026-03-0213GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,388,638
11.000%
195,049increase
(+8.89%)
Filing
History
2026-02-20
8:22 pm
Sale
2026-02-1913GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,193,589
10.090%
-75,000decrease
(-3.31%)
Filing
History
2026-02-20
8:13 pm
Purchase
2026-02-1913GQ32 BIO INC
QTTB
Opaleye Management Inc.1,256,228
8.650%
1,256,228increase
(New Position)
Filing
History
2026-02-20
4:10 pm
Purchase
2026-02-1913GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,268,589
10.430%
197,805increase
(+9.55%)
Filing
History
2026-02-06
4:05 pm
Purchase
2025-12-3113GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.2,070,784
9.520%
195,642increase
(+10.43%)
Filing
History
2026-01-23
4:05 pm
Sale
2025-12-3113GCODEXIS INC
CDXS
Opaleye Management Inc.6,789,738
7.520%
-2,198,251decrease
(-24.46%)
Filing
History
2025-12-19
4:05 pm
Purchase
2025-12-1213GREZOLUTE INC
RZLT
Opaleye Management Inc.4,912,900
5.300%
4,912,900increase
(New Position)
Filing
History
2025-12-05
4:05 pm
Purchase
2025-12-0313GCODEXIS INC
CDXS
Opaleye Management Inc.8,987,989
9.950%
1,463,989increase
(+19.46%)
Filing
History
2025-11-17
4:15 pm
Purchase
2025-11-1313GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.367,367
13.190%
162,532increase
(+79.35%)
Filing
History
2025-11-14
4:05 pm
Purchase
2025-09-3013GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.204,835
7.350%
65,449increase
(+46.96%)
Filing
History
2025-10-17
4:05 pm
Purchase
2025-10-1013GKARYOPHARM THERAPEUTICS INC CO
KPTI
Opaleye Management Inc.1,569,002
9.480%
1,569,002increase
(New Position)
Filing
History
2025-10-03
4:05 pm
Purchase
2025-10-0113GALPHA COGNITION INC NE
ACOG
Opaleye Management Inc.1,875,142
8.970%
1,875,142increase
(New Position)
Filing
History
2025-08-29
4:05 pm
Purchase
2025-08-2213GSOL-GEL TECHNOLOGIES LTD SHS N
SLGL
Opaleye Management Inc.139,386
5.000%
139,386increase
(New Position)
Filing
History
2025-08-29
4:05 pm
Purchase
2025-08-2913GLARIMAR THERAPEUTICS INC
LRMR
Opaleye Management Inc.4,110,000
4.800%
157,591increase
(+3.99%)
Filing
History
2025-04-28
4:05 pm
Sale
2025-03-3113GPROTARA THERAPEUTICS INC
TARA
Opaleye Management Inc.1,730,000
4.710%
-95,000decrease
(-5.21%)
Filing
History
2025-04-16
5:11 pm
Purchase
2025-04-0913GLARIMAR THERAPEUTICS INC
LRMR
Opaleye Management Inc.3,952,409
6.170%
2,392,409increase
(+153.36%)
Filing
History
2025-02-14
06:46 am
Sale
2024-12-3113GOCULAR THERAPEUTIX INC
OCUL
Opaleye Management Inc.4,342,500
2.760%
-1,727,500decrease
(-28.46%)
Filing
History
2025-02-14
06:42 am
Purchase
2024-12-3113GIBIO INC PAR $0.001
IBIO
Opaleye Management Inc.750,000
7.600%
100,000increase
(+15.38%)
Filing
History
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