Sec Form 3 Filing - THOMAS CYNTHIA J @ NEUROCRINE BIOSCIENCES INC - 2004-03-01

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person THOMAS CYNTHIA J 2. Issuer Name and Ticker or Trading Symbol NEUROCRINE BIOSCIENCES INC [ NBIX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) VP, Human Resources (Last) (First) (Middle) 10555 SCIENCE CENTER DRIVE 3. Date of Earliest Transaction (MM/DD/YY) 03/01/2004 (Street) SAN DIEGO, CA92121 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 4,170 D Common Stock ( 1 ) 500 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option $ 6.5 09/19/1998 08/19/2008 Common Stock 5,000 D Stock Option $ 4.875 07/01/1999 06/01/2009 Common Stock 14,000 D Stock Option $ 19.4375 05/06/2000 04/06/2010 Common Stock 20,000 D Stock Option $ 24.33 05/18/2001 04/18/2011 Common Stock 10,000 D Stock Option $ 35.14 06/24/2001 05/24/2011 Common Stock 15,000 D Stock Option $ 36.79 03/07/2002 02/07/2012 Common Stock 30,000 D Stock Option $ 48.51 06/22/2003 05/22/2013 Common Stock 15,000 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other THOMAS CYNTHIA J 10555 SCIENCE CENTER DRIVE SAN DIEGO, CA92121 VP, Human Resources Signatures Paul W. Hawran, By Power of Attorney 03/03/2004 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents common stock shares granted to Reporting Person of which 1/48th of the shares becomes vested on April 1, 2004; an additional 1/48th of the shares becomes vested each month thereafter.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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