Sec Form 4 Filing - RODRIGUEZ EDWARD @ IDEC PHARMACEUTICALS CORP / DE - 2003-09-02

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person RODRIGUEZ EDWARD 2. Issuer Name and Ticker or Trading Symbol IDEC PHARMACEUTICALS CORP / DE [ IDPH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) VP and Controller (Last) (First) (Middle) 3030 CALLAN RD 3. Date of Earliest Transaction (MM/DD/YY) 09/02/2003 (Street) SAN DIEGO, CA92121 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/31/2003 J( 1 ) 40 A $ 29.087 5,266 D Common Stock 06/30/2003 J( 1 ) 18 A $ 28.866 5,284 D Common Stock 08/29/2003 M 1,490 A $ 4.3542 6,774 D Common Stock 08/29/2003 S 1,490 D $ 34.6803 5,284 D Common Stock 08/29/2003 M 680 A $ 7.4167 5,964 D Common Stock 08/29/2003 S 680 D $ 34.6803 5,284 D Common Stock 08/29/2003 M 2,100 A $ 5.25 7,384 D Common Stock 08/29/2003 S 2,100 D $ 34.6803 5,284 D Common Stock 08/29/2003 M 4,250 A $ 9.5104 9,534 D Common Stock 08/29/2003 S 4,250 D $ 34.6803 5,284 D Common Stock 08/29/2003 M 9,105 A $ 16.2604 14,389 D Common Stock 08/29/2003 S 9,105 D $ 34.6803 5,284 D Common Stock 09/02/2003 S 9,895 D $ 33.8351 7,100 I by Trust

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Incentive Stock Option (right to buy) ( 2 ) $ 4.3542 08/29/2003 M 1,490 ( 3 ) 04/16/1997( 3 ) 04/23/2006 Common Stock 1,490 ( 2 ) 8,510 D Incentive Stock Option (right to buy) ( 2 ) $ 5.25 08/29/2003 M 2,100 ( 4 ) 04/01/1999( 4 ) 05/20/2008 Common Stock 2,100 ( 2 ) 2,940 D Incentive Stock Option (right to buy) ( 2 ) $ 7.4167 08/29/2003 M 680 ( 5 ) 12/16/1998( 5 ) 02/19/2008 Common Stock 680 ( 2 ) 24,920 D Incentive Stock Option (right to buy) ( 2 ) $ 9.5104 08/29/2003 M 4,250 ( 6 ) 04/01/2000( 6 ) 04/20/2009 Common Stock 4,250 ( 2 ) 10,750 D Incentive Stock Option (right to buy) ( 2 ) $ 16.2604 08/29/2003 M 9,105 ( 7 ) 09/16/2000( 7 ) 09/23/2009 Common Stock 9,105 ( 2 ) 8,895 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other RODRIGUEZ EDWARD 3030 CALLAN RD SAN DIEGO, CA92121 VP and Controller Signatures By: Pamela A. Blas For: Edward Rodriguez 09/03/2003 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Acquisition of shares under the Employee Stock Purchase Plan in a transaction exempt under SEC Rule 16b-3(c). ( 2 )Granted under Issuer's Employee Stock Option Plan, in an exempt transaction under SEC rule 16b-3(d). ( 3 )Option was originally granted for 12,000 shares and became exercisable as follows: 25% of the optioned shares on 4/16/97 and as to the balance of the shares in 36 equal monthly installments thereafter. ( 4 )Option was originally granted for 5,040 shares and became exercisable as follows: 25% of the optioned shares on 4/1/99 and as to the balance of the shares in 36 equal monthly installments thereafter. ( 5 )Option was originally granted for 33,600 shares and became exercisable as follows: 25% of the optioned shares on 12/16/98 and as to the balance of the shares in 36 equal monthly installments thereafter. ( 6 )Option was originally granted for 15,000 shares and became exercisable as follows: 25% of the optioned shares on 4/1/00 and as to the balance of the shares in 36 equal monthly installments thereafter. ( 7 )Option was originally granted for 18,000 shares and became exercisable as follows: 25% of the optioned shares on 9/16/00 and as to the balance of the shares in 36 equal monthly installments thereafter.

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