Sec Form 4/A Filing - OSSER LEONARD @ MILESTONE SCIENTIFIC INC. - 2020-08-04

FORM 4/A Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person OSSER LEONARD 2. Issuer Name and Ticker or Trading Symbol MILESTONE SCIENTIFIC INC. [ MLSS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Interim CEO (Last) (First) (Middle) C/O MILESTONE SCIENTIFIC INC., 425 EAGLE ROCK AVENUE 3. Date of Earliest Transaction (MM/DD/YY) 08/04/2020 (Street) ROSELAND, NJ07068 4. If Amendment, Date Original Filed (MM/DD/YY) 08/05/2020 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, Par Value $0.001 08/04/2020 J 133,333 D $ 2.1 3,927,727 ( 1 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other OSSER LEONARD C/O MILESTONE SCIENTIFIC INC. 425 EAGLE ROCK AVENUE ROSELAND, NJ07068 X Interim CEO Signatures /s/ Leonard Osser 01/12/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )1,492,354 of these shares are issuable to the reporting person at the termination of employment.

Remarks: This amendment, dated January 12, 2021, to the Form 4 Report filed August 5, 2020 of the reporting person is being made to correct the characterization of the transaction. On August 4, 2020, the reporting person transferred 133,333 shares of Milestone Scientific Inc. ("Milestone") to Care Pro Solutions, Inc. ("Care Pro"), a Delaware corporation. The reporting person as of August 4, 2020 and thereafter was not a controlling stockholder, director or officer of Care Pro nor held or holds any investment control over the portfolio of securities that Care Pro held or holds. Therefore, the reporting person is able to take advantage of the non-exclusive safe harbor of Rule 16a-1(a)(2)(iii) under which the reporting person is not deemed the beneficial owner of a corporation's portfolio. In addition, to the extent that in the future the reporting person is no longer able to take advantage of the exclusion of beneficial ownership of the portfolio of securities held by Care Pro as provided by Rule 16a-1(a)(2)(iii), the transaction of August 4, 2020 will be a change of ownership from direct to indirect. The previously reported purchase of Milestone common stock on the Form 4 filed on August 5, 2020 was therefore not reported consistent with non-exclusive safe harbor of Rule 16a-1(a)(2)(iii) or the correct characterization of the mere change from direct to indirect ownership

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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