Sec Form 4 Filing - CARDONA JAIME A @ APPLIED DNA SCIENCES INC - 2004-04-22

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person CARDONA JAIME A 2. Issuer Name and Ticker or Trading Symbol APPLIED DNA SCIENCES INC [ APDN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner _____ Officer (give title below) X __ Other (specify below) Past Secretary (Last) (First) (Middle) 1285 N CRESCENT HEIGHTS BLVD D 3. Date of Earliest Transaction (MM/DD/YY) 04/22/2004 (Street) LOS ANGELES, CA90505 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/22/2004 S( 1 ) 2,800 D ( 2 ) $ 2 131,550 D Common Stock 04/22/2004 S( 1 ) 1,700 D ( 2 ) $ 2.15 128,750 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other CARDONA JAIME A 1285 N CRESCENT HEIGHTS BLVD D LOS ANGELES, CA90505 Past Secretary Signatures Jaime Cardona 05/03/2004 Signature of Reporting Person Date

Explanation of Responses:

( 1 )In November of 2002, Applied DNA Sciences, Inc. (the "Company") created a compensation plan for founders, employees and consultants which was filed the Securities and Exchange Commission on a Form S-8 (the "Plan") which was later amended in January of 2003. The Plan provides an alternative method of compensating individuals whose services are important to the ongoing development of the Company. Shares are issued to eligible recipients in lieu of cash compensation in accordance with employment or consulting agreements entered into between them and the Company. Such recipients, including the reporting person, signed leak out agreements with the Company, limiting the number of shares they are permitted to sell in a thirty day period. Compensation shares such as these are exempt from the short swing rule by reason of Rule 16(b)3. ( 2 )A Form 144 was properly filed prior to making this sale.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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