Sec Form 4 Filing - LABRUM RONALD K @ CARDINAL HEALTH INC - 2006-05-16

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person LABRUM RONALD K 2. Issuer Name and Ticker or Trading Symbol CARDINAL HEALTH INC [ CAH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) CEO-Supply Chain Svcs. (Last) (First) (Middle) 1430 WAUKEGAN ROAD 3. Date of Earliest Transaction (MM/DD/YY) 05/16/2006 (Street) MCGAW PARK, IL60085 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 05/16/2006 M 37,500 A $ 31.167 73,582 D Common Shares 05/16/2006 S 37,300 D $ 68.3 36,282 D Common Shares 05/16/2006 S 200 D $ 68.43 36,082 D Common Shares 5,774 I By 401(k) plan Common Shares 2,816 I By ESPP

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Option (right to buy) ( 1 ) $ 31.167 05/16/2006 M 1 11/15/2002 11/15/2009 Common Shares 37,500 ( 2 ) 0 D Option (right to buy) ( 1 ) $ 47.33 03/01/2002 03/01/2009 Common Shares 18,600 1 D Option (right to buy) ( 1 ) $ 66.083 11/20/2003 11/20/2010 Common Shares 31,500 1 D Option (right to buy) ( 1 ) $ 68.1 11/19/2004 11/19/2011 Common Shares 44,604 1 D Option (right to buy) ( 1 ) $ 67.9 11/18/2005 11/18/2012 Common Shares 53,019 1 D Option (right to buy) ( 1 ) $ 61.38 11/17/2006 11/17/2013 Common Shares 25,000 1 D Option (right to buy) ( 1 ) $ 61.38 11/17/2006 11/17/2013 Common Shares 60,280 1 D Option (right to buy) ( 1 ) $ 44.15 08/23/2007 08/23/2014 Common Shares 105,000 1 D Option (right to buy) ( 1 ) $ 58.88 ( 3 ) 09/02/2012 Common Shares 84,288 1 D Option (right to buy) ( 1 ) $ 62.38 ( 4 ) 09/15/2012 Common Shares 84,288 1 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other LABRUM RONALD K 1430 WAUKEGAN ROAD MCGAW PARK, IL60085 CEO-Supply Chain Svcs. Signatures Ronald K. Labrum 05/17/2006 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan. ( 2 )Stock option was disposed of in connection with its exercise for no additional consideration beyond the option shares. ( 3 )Stock option vests in four equal annual installments beginning on 9/2/2006. ( 4 )Stock option vests in four equal annual installments beginning on 9/15/2006.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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