Sec Form 3 Filing - Carlyle Group Management L.L.C. @ Ortho Clinical Diagnostics Holdings plc - 2021-01-27

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Carlyle Group Management L.L.C. 2. Issuer Name and Ticker or Trading Symbol Ortho Clinical Diagnostics Holdings plc [ OCDX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O THE CARLYLE GROUP INC., 1001 PENNSYLVANIA AVENUE NW , SUITE 220 3. Date of Earliest Transaction (MM/DD/YY) 01/27/2021 (Street) WASHINGTON, DC20004-2505 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 143,406,000 I See footnote ( 1 ) ( 2 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Carlyle Group Management L.L.C. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X Carlyle Group Inc. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X Carlyle Holdings II GP L.L.C. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X Carlyle Holdings II L.L.C. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X CG Subsidiary Holdings L.L.C. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X TC Group Cayman Investment Holdings, L.P. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X TC Group Cayman Investment Holdings Sub L.P. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X TC Group VI Cayman, L.L.C. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X TC Group VI Cayman, L.P. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X Carlyle Partners VI Cayman Holdings, L.P. C/O THE CARLYLE GROUP INC. 1001 PENNSYLVANIA AVENUE NW , SUITE 220 WASHINGTON, DC20004-2505 X Signatures Carlyle Group Management L.L.C., By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Chief Financial Officer 01/27/2021 Signature of Reporting Person Date The Carlyle Group Inc., By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Chief Financial Officer 01/27/2021 Signature of Reporting Person Date Carlyle Holdings II GP L.L.C., By: The Carlyle Group Inc., its sole member, By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Chief Financial Officer 01/27/2021 Signature of Reporting Person Date Carlyle Holdings II L.L.C., By /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Chief Financial Officer 01/27/2021 Signature of Reporting Person Date CG Subsidiary Holdings L.L.C., By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Authorized Person 01/27/2021 Signature of Reporting Person Date TC Group Cayman Investment Holdings, L.P., By: CG Subsidiary Holdings L.L.C., its general partner, By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Authorized Person 01/27/2021 Signature of Reporting Person Date TC Group Cayman Investment Holdings Sub L.P., By: TC Group Cayman Investment Holdings, L.P., its general partner, By: CG Subsidiary Holdings L.L.C., its general partner, By: /s/ Anne Frederick, Attorney-in-fact for Curtis L. Buser, Authorized Person 01/27/2021 Signature of Reporting Person Date TC Group VI Cayman, L.L.C., By: /s/ Jeremy W. Anderson, Authorized Person 01/27/2021 Signature of Reporting Person Date TC Group VI Cayman, L.P., By: /s/ Jeremy W. Anderson, Authorized Person 01/27/2021 Signature of Reporting Person Date Carlyle Partners VI Cayman Holdings, L.P., By: /s/ Jeremy W. Anderson, Authorized Person 01/27/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Reflects ordinary shares held of record by Carlyle Partners VI Cayman Holdings, L.P. (the "Carlyle Investor"). Carlyle Group Management L.L.C. holds an irrevocable proxy to vote a majority of the shares of The Carlyle Group Inc. ("Carlyle"), a publicly traded company listed on Nasdaq. Carlyle is the sole member of Carlyle Holdings II GP L.L.C., which is the managing member of Carlyle Holdings II L.L.C., which, with respect to the securities reported herein, is the managing member of CG Subsidiary Holdings L.L.C., which is the general partner of TC Group Cayman Investment Holdings, L.P., which is the general partner of TC Group Cayman Investment Holdings Sub L.P., which is the sole member of TC Group VI Cayman, L.L.C., which is the general partner of TC Group VI Cayman, L.P., which is the general partner of the Carlyle Investor. ( 2 )Voting and investment determinations with respect to the ordinary shares held of record by the Carlyle Investor are made by an investment committee of TC Group VI Cayman, L.P. Accordingly, each of the foregoing entities may be deemed to share beneficial ownership of the securities held of record by the Carlyle Investor. Each of them disclaims beneficial ownership of such securities.

Remarks: Exhibit 24 - Power of Attorney.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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