Sec Form 4 Filing - Semigran Marc @ Renovacor, Inc. - 2021-12-20

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Semigran Marc 2. Issuer Name and Ticker or Trading Symbol Renovacor, Inc. [ RCOR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Medical Officer (Last) (First) (Middle) C/O RENOVACOR, INC., P.O. BOX 8142 3. Date of Earliest Transaction (MM/DD/YY) 12/20/2021 (Street) GREENWICH, CT06836 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option $ 10.83 12/20/2021 A 88,991 ( 1 ) 06/01/2031 Common Stock 88,991 $ 0 88,991 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Semigran Marc C/O RENOVACOR, INC. P.O. BOX 8142 GREENWICH, CT06836 Chief Medical Officer Signatures By: /s/ Joseph Carroll, as attorney- in-fact 12/22/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )On September 2, 2021, the Reporting Person was granted a stock option that will vest and become exercisable in full on December 2, 2021, subject to the achievement of certain performance based milestones set forth in theEmployment Agreement by and between the Issuer and the Reporting Person, dated May 5, 2021 (with the achievement of such performance based milestones subject to the approval of the Compensation Committee of the Boardof Directors of the Issuer), and the continuous service of the Reporting Person on such vesting date. On December 20, 2021, the Compensation Committee of the Board of Directors of the Issuer determined that the performancecriteria was met, resulting in the vesting of the option as to 88,991 shares as of such vesting date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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