Sec Form 3 Filing - MALLIK AMEET @ ADC Therapeutics SA - 2024-01-02

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person MALLIK AMEET 2. Issuer Name and Ticker or Trading Symbol ADC Therapeutics SA [ ADCT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) 430 MOUNTAIN AVENUE, SUITE 404 3. Date of Earliest Transaction (MM/DD/YY) 01/02/2024 (Street) NEW PROVIDENCE, NJ07974 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 1,197,079 ( 1 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Options (Right to Buy) $ 10.95 ( 2 ) 05/06/2032 Common Shares 1,067,961 D Stock Options (Right to Buy) $ 1.99 ( 3 ) 03/22/2033 Common Shares 625,000 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other MALLIK AMEET 430 MOUNTAIN AVENUE, SUITE 404 NEW PROVIDENCE, NJ07974 X Chief Executive Officer Signatures /s/ Ameet Mallik 01/02/2024 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Includes 990,000 Common Shares to be delivered in settlement of a restricted share unit award ("RSUs") which vests 50% on the one-year anniversary of the grant date, which grant date is December 6, 2023, and on the two-year anniversary of the grant date, and 207,079 RSUs granted on May 2022 which vest 1/3 on each of the first three anniversaries of the grant date. Both awards are subject to continued service through the designated vesting event. ( 2 )This option vests over four years from May 6, 2022, with 1/4 vesting on the first anniversary of such date, and the remainder vesting monthly in 36 equal installments, subject to continued service through each such vesting date. ( 3 )This option vests over four years from March 22, 2023, with 1/4 vesting on the first anniversary of such date, and the remainder vesting monthly in 36 equal installments, subject to continued service through each such vesting date.

Remarks: Exhibit List - Exhibit 24 - Power of Attorney

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

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