Sec Form 4 Filing - Tamaro Renato @ STERIS plc - 2021-08-26

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Tamaro Renato 2. Issuer Name and Ticker or Trading Symbol STERIS plc [ STE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) V.P. & Corporate Treasurer (Last) (First) (Middle) C/O 70 SIR JOHN ROGERSON'S QUAY 3. Date of Earliest Transaction (MM/DD/YY) 08/26/2021 (Street) DUBLIN, L22 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 08/26/2021 M 149 A $ 69.72 5,521 ( 1 ) D Ordinary Shares 08/26/2021 M 300 A $ 77.07 5,821 ( 1 ) D Ordinary Shares 08/26/2021 M 1,000 A $ 114.22 6,821 ( 1 ) D Ordinary Shares 08/26/2021 S 1,449 D $ 213.63 ( 2 ) 5,372 ( 1 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Employee Stock Option (right to buy) $ 69.72 08/26/2021 M 149 ( 3 ) 06/01/2026 Ordinary Shares 149 $ 0 0 D Employee Stock Option (right to buy) $ 77.07 08/26/2021 M 300 ( 4 ) 05/30/2027 Ordinary Shares 300 $ 0 0 D Employee Stock Option (right to buy) $ 114.22 08/26/2021 M 1,000 ( 5 ) 05/31/2028 Ordinary Shares 1,000 $ 0 436 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Tamaro Renato C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN, L22 V.P. & Corporate Treasurer Signatures /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 08/27/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )2,200 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 484 on May 31, 2022; 556 on May 31, 2023; 584 on June 3, 2024; 432 on June 3, 2024 and 144 on June 2, 2025. ( 2 )Price reflects a weighted average sale price for multiple transactions ranging from $213.5553 to $213.7250 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price. ( 3 )This option is part of an option to purchase 596 STERIS ordinary shares, which are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 596 Old STERIS ordinary shares for $69.72 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law. ( 4 )This option is part of an option to purchase 600 STERIS ordinary shares, which are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 600 Old STERIS ordinary shares for $77.07 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law. ( 5 )This option is part of an option to purchase 2,872 STERIS ordinary shares, of which 1,718 shares are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 2,872 Old STERIS ordinary shares for $114.22 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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