Sec Form 3/A Filing - WIRTH PETER @ Zai Lab Ltd - 2021-01-01

FORM 3/A Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person WIRTH PETER 2. Issuer Name and Ticker or Trading Symbol Zai Lab Ltd [ ZLAB] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O ZAI LAB LIMITED, 4560 JINKE ROAD, BLDG 1, 4TH FLOOR 3. Date of Earliest Transaction (MM/DD/YY) 01/01/2021 (Street) PUDONG, SHANGHAI, F4201210 4. If Amendment, Date Original Filed (MM/DD/YY) 01/04/2021 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 335,000 ( 1 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other WIRTH PETER C/O ZAI LAB LIMITED 4560 JINKE ROAD, BLDG 1, 4TH FLOOR PUDONG, SHANGHAI, F 4201210 X Signatures By: /s/ Bruce Blefeld, Attorney-in-Fact* 01/19/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The original Form 3 filed on January 4, 2021 correctly reported the amount of securities directly owned by the Reporting Person as of January 4, 2021 as 335,000 shares. The first Amended Form 3 filed on January 19, 2021 incorrectly reported that the amount of securities directly owned by the Reporting Person as of January 4, 2021 was 35,000 shares. This second Amended Form 3 is being filed to re-state the original Form 3. The correct number of shares directly owned by the Reporting Person as of January 4, 2021 was 335,000.

Remarks: *Power of Attorney on file

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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