Sec Form 4 Filing - Kadia Siddhartha @ Berkeley Lights, Inc. - 2022-03-10

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Kadia Siddhartha 2. Issuer Name and Ticker or Trading Symbol Berkeley Lights, Inc. [ BLI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O BERKELEY LIGHTS, INC., 5858 HORTON STREET, SUITE 320 3. Date of Earliest Transaction (MM/DD/YY) 03/10/2022 (Street) EMERYVILLE, CA94608 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/10/2022 A 1,017,177( 1 ) A $ 0 1,022,077 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 5.69 03/10/2022 A 339,059 ( 2 ) 03/09/2032 Common Stock 339,059 $ 0 339,059 D Stock Option (Right to Buy) $ 5.69 03/10/2022 A 678,118 ( 3 ) 03/09/2032 Common Stock 678,118 $ 0 678,118 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Kadia Siddhartha C/O BERKELEY LIGHTS, INC. 5858 HORTON STREET, SUITE 320 EMERYVILLE, CA94608 X Chief Executive Officer Signatures /s/ Stuart L. Merkadeau, Attorney-in-fact for Siddhartha Kadia 03/22/2022 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents an award of restricted stock units which will vest in twelve (12) equal quarterly installments beginning from the date that is one quarterly anniversary after March 9, 2022 (the "Appointment Date"). ( 2 )The stock option will vest in twelve (12) equal quarterly installments on each quarterly anniversary from the Appointment Date. ( 3 )The stock option will vest subject to both a service-based requirement and a performance-based requirement, where (i) the service-based requirement shall be satisfied with respect to 20% of the stock option shares on each anniversary of the Appointment Date, and (ii) the performance-based requirement will be satisfied with respect to 20% of the stock options shares based on achieving each of the stock option price goals of 200%, 400%, 800%, 1500% and 2000% of $5.93, which such stock price goals must be achieved by the seventh anniversary of the Appointment Date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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