Sec Form 4 Filing - Vizirgianakis Stavros G. @ Bioventus Inc. - 2021-10-29

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Vizirgianakis Stavros G. 2. Issuer Name and Ticker or Trading Symbol Bioventus Inc. [ BVS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 4721 EMPEROR BOULEVARD, SUITE 100 3. Date of Earliest Transaction (MM/DD/YY) 10/29/2021 (Street) DURHAM, NC27703 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 7.57 10/29/2021 A 26,179 ( 1 ) 02/03/2025 Class A Common Stock 26,179 ( 2 ) ( 3 ) 26,179 D Stock Option (Right to Buy) $ 3.33 10/29/2021 A 6,544 ( 1 ) 12/03/2023 Class A Common Stock 6,544 ( 2 ) ( 3 ) 6,544 D Stock Option (Right to Buy) $ 4.13 10/29/2021 A 19,634 ( 1 ) 02/04/2026 Class A Common Stock 19,634 ( 2 ) ( 3 ) 19,634 D Stock Option (Right to Buy) $ 12.27 10/29/2021 A 34,905 ( 1 ) 11/22/2029 Class A Common Stock 34,905 ( 2 ) ( 3 ) 34,905 D Stock Option (Right to Buy) $ 5.63 10/29/2021 A 347,323 ( 1 ) 05/13/2030 Class A Common Stock 347,323 ( 2 ) ( 3 ) 347,323 D Stock Option (Right to Buy) $ 7.78 10/29/2021 A 89,001 ( 1 ) 06/29/2030 Class A Common Stock 89,001 ( 2 ) ( 3 ) 89,001 D Stock Option (Right to Buy) $ 12.71 10/29/2021 A 261,794 ( 1 ) 06/29/2030 Class A Common Stock 261,794 ( 2 ) ( 3 ) 261,794 D Restricted Stock Units ( 4 ) 10/29/2021 A 2,895 ( 5 ) ( 5 ) Class A Common Stock 2,895 $ 0 2,895 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Vizirgianakis Stavros G. 4721 EMPEROR BOULEVARD, SUITE 100 DURHAM, NC27703 X Signatures /s/ Anthony D'Adamio, Attorney-in-Fact 11/02/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )This option is fully vested and exercisable. ( 2 )Pursuant to the Agreement and Plan of Merger, dated as of July 29, 2021 (the "Merger Agreement"), each option to purchase Misonix Inc. ("Misonix") common stock (a "Misonix Option"), whether vested or unvested, that was outstanding immediately prior to the effective time of the transactions contemplated by the Merger Agreement (the "Effective Time"), was converted into an option to acquire the number of shares of Class A common stock of the Issuer (an "Issuer Option") equal to the product of (i) the number of shares of Misonix common stock subject to such Misonix Option immediately prior to the First Effective Time (as defined in the Merger Agreement); ( 3 )(continued from footnote 2) by (B) the Option Exchange Ratio (as defined in the Merger Agreement), rounded down to the nearest whole number of sharesof the Issuer's Class A common stock, at an exercise price per share equal to the quotient obtained by dividing the per share exercise price of the MisonixOption by the Option Exchange Ratio, rounded up to the nearest whole cent. ( 4 )Each restricted stock unit represents a contingent right to receive one share of Class A common stock ( 5 )The restricted stock units shall vest and become exercisable in three equal installments, with the first installment vesting and becoming exercisableon the earlier of (i) the day immediately preceding the date of the Issuer's first annual meeting of stockholders following the date of grant and (ii)the first anniversary of the date of grant (such earlier date, the "Installment Vesting Date") and the second and third installments vesting andbecoming exercisable on the first and second anniversaries of the Installment Vesting Date, respectively, in each case subject to the ReportingPerson continuing in service on the Issuer's Board of Directors through the applicable vesting date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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