Sec Form 4 Filing - Levy Guy @ Parabilis Medicines, Inc. - 2026-06-11

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Levy Guy 2. Issuer Name and Ticker or Trading Symbol Parabilis Medicines, Inc. [ PBLS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O SOLEUS CAPITAL MANAGEMENT, L.P., 100 FIELD POINT ROAD, SUITE 200 3. Date of Earliest Transaction (MM/DD/YY) 06/11/2026 (Street) GREENWICH, CT06830 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, par value $0.0001 per share 06/11/2026 P 375,000 A $ 20 1,027,000 I ( 4 ) See footnote Common Stock, par value $0.0001 per share 06/11/2026 P 125,000 A $ 20 652,000 I ( 2 ) ( 3 ) See footnote Common Stock, par value $0.0001 per share 06/11/2026 C 527,070 A $ 9.48 527,070 I ( 2 ) ( 3 ) See footnote

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series F Preferred Stock $ 9.48 06/11/2026 C 527,070 ( 1 ) ( 1 ) Common Stock 527,070 $ 0 0 I ( 2 ) ( 3 ) See footnote

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Levy Guy C/O SOLEUS CAPITAL MANAGEMENT, L.P. 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Private Equity Fund III, L.P. 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Private Equity GP III, LLC 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus PE GP III, LLC 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Capital Management, L.P. 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus GP, LLC 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Capital Master Fund, L.P. 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Capital, LLC 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Soleus Capital Group, LLC 100 FIELD POINT ROAD, SUITE 200 GREENWICH, CT06830 X Signatures /s/ Guy Levy 06/29/2026 Signature of Reporting Person Date Soleus Private Equity Fund III, L.P., /s/ Guy Levy, Managing Member of Soleus PE GP III, LLC, which is the Manager of Soleus Private Equity GP III, LLC, which is the General Partner of Soleus Private Equity Fund III, L.,P. 06/29/2026 Signature of Reporting Person Date Soleus Private Equity GP III, LLC, /s/ Guy Levy, Managing Member of Soleus PE GP III, LLC, which is the Manager of Soleus Private Equity GP III, LLC 06/29/2026 Signature of Reporting Person Date Soleus PE GP III, LLC, /s/ Guy Levy, Managing Member 06/29/2026 Signature of Reporting Person Date Soleus Capital Management, L.P., /s/ Guy Levy, Managing Member of the General Partner of Soleus Capital Management, L.P. 06/29/2026 Signature of Reporting Person Date Soleus GP, LLC, /s/ Guy Levy, Managing Member 06/29/2026 Signature of Reporting Person Date Soleus Capital Master Fund, L.P., /s/ Guy Levy, Managing Member of the General Partner of Soleus Capital Master Fund, L.P. 06/29/2026 Signature of Reporting Person Date Soleus Capital, LLC, /s/ Guy Levy, Managing Member of Soleus Capital, LLC 06/29/2026 Signature of Reporting Person Date Soleus Capital Group, LLC, /s/ Guy Levy, Managing Member 06/29/2026 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The Series F Preferred Stock automatically converted into shares of the common stock of the issuer immediately prior to the closing of the issuer's initial public offering without payment of consideration and had no expiration date. ( 2 )The reportable securities are owned directly by Soleus Private Equity Fund III, L.P. ("Soleus PE"). Soleus Private Equity GP III, LLC ("Soleus PE GP") is the sole general partner of Soleus PE, Soleus PE GP III, LLC is the sole manager of Soleus PE GP, Soleus Capital Management, L.P. ("SCM") is the investment manager for Soleus PE, and Soleus GP, LLC ("Soleus GP") is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus PE GP III, LLC and Soleus GP. ( 3 )Each of Mr. Levy, Soleus PE GP III, LLC, Soleus PE GP, SCM and Soleus GP disclaims beneficial ownership of the securities held by Soleus PE other than for the purpose of determining their obligations under Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such securities for any other purpose, except to the extent of their respective pecuniary interests therein. ( 4 )The reportable securities are owned directly by Soleus Capital Master Fund, L.P. ("MF"). Soleus Capital LLC is the sole general partner of MF, Soleus Capital Group, LLC ("SCG") is the sole managing member of Soleus Capital, LLC, SCM is the investment manager of MF, and Soleus GP is the sole general partner of SCM. Guy Levy is the sole managing member of each of SCG and Soleus GP. Each of Mr. Levy, SCG, Soleus Capital LLC, SCM and Soleus GP disclaims beneficial ownership of the securities held by MF other than for the purpose of determining their obligations under Section 16 of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such securities for any other purpose, except to the extent of their respective pecuniary interests therein.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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