Sec Form 4 Filing - Collins Cynthia @ Editas Medicine, Inc. - 2019-08-19

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Collins Cynthia 2. Issuer Name and Ticker or Trading Symbol Editas Medicine, Inc. [ EDIT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) CEO (Last) (First) (Middle) C/O EDITAS MEDICINE, INC., 11 HURLEY ST. 3. Date of Earliest Transaction (MM/DD/YY) 08/19/2019 (Street) CAMBRIDGE, MA02141 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 08/19/2019 A 8,283 A $ 0 16,566 ( 1 ) D Common Stock 08/19/2019 S( 2 ) 5,193 D $ 25.83 11,373 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Re porting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Collins Cynthia C/O EDITAS MEDICINE, INC. 11 HURLEY ST. CAMBRIDGE, MA02141 X CEO Signatures /s/ Cynthia Collins 08/21/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The reported transaction involved the Reporting Peron's receipt of 8,283 shares of common stock on August 19, 2019 in connection with the vesting of a restricted stock unit award. Such amount includes (i) 8,283 shares of common stock received by the Reporting Person on August 19, 2019 that was previously reported on Table II of a Form 4 filed by the Reporting Person with the SEC on February 4, 2019 and (ii) 8,283 shares of common stock received by the Reporting Person in connection with a restricted stock unit award that was previously reported in Table 1 of a Form 4 filed by the Reporting Person with the SEC on August 7, 2019. ( 2 )The sales reported in this Form 4 were effected pursuant to a durable automatic sales instruction letter entered into between the Reporting Person and the issuer in connection with the Reporting Person receiving restricted stock unit awards from the issuer, and represent the sale of shares necessary to meet tax withholding obligations as a result of vesting in restricted stock units on August 19, 2019. The sales do not represent a discretionary trade by the Reporting Person.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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