Sec Form 4 Filing - Omega Fund IV, L.P. @ Kezar Life Sciences, Inc. - 2018-06-25

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Omega Fund IV, L.P. 2. Issuer Name and Ticker or Trading Symbol Kezar Life Sciences, Inc. [ KZR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner _____ Officer (give title below) X __ Other (specify below) Former 10% Owner (Last) (First) (Middle) 185 DARTMOUTH STREET 3. Date of Earliest Transaction (MM/DD/YY) 06/25/2018 (Street) BOSTON, MA02116 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 06/25/2018 C 315,489 A $ 0 ( 1 ) 315,489 D Common Stock 06/25/2018 C 315,489 A $ 0 ( 1 ) 315,489 I ( 2 ) By Omega IV Common Stock 06/25/2018 C 377,783 A $ 0 ( 3 ) 693,272 D Common Stock 06/25/2018 C 377,783 A $ 0 ( 3 ) 693,272 I ( 2 ) By Omega IV

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series A Redeemable Convertible Preferred Stock ( 1 ) 06/25/2018 C 315,489 ( 1 ) ( 1 ) Common Stock 315,489 $ 0 0 D Series A Redeemable Convertible Preferred Stock ( 1 ) 06/25/2018 C 315,489 ( 1 ) ( 1 ) Common Stock 315,489 $ 0 0 I ( 2 ) By Omega IV Series B Redeemable Convertible Preferred Stock ( 3 ) 06/25/2018 C 377,783 ( 3 ) ( 3 ) Common Stock 377,783 $ 0 0 D Series B Redeemable Convertible Preferred Stock ( 3 ) 06/25/2018 C 377,783 ( 3 ) ( 3 ) Common Stock 377,783 $ 0 0 I ( 2 ) By Omega IV

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Omega Fund IV, L.P. 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Omega Fund IV GP, L.P. 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Omega Fund IV G.P. Manager, Ltd. 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Stampacchia Otello 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Lim Richard J. 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Paster Anne-Mari 185 DARTMOUTH STREET BOSTON, MA02116 Former 10% Owner Signatures By: /s/ Anne-Mari Paster, Signature of Anne-Mari Paster as an authorized signatory of each Reporting Person 06/25/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The Series A Redeemable Convertible Preferred Stock ("Series A") converted automatically into shares of the issuer's common stock on a one-for-one basis upon the completion of the issuer's public offering of common stock pursuant the issuer's amended registration statement under the Securities Act of 1933, as amended, filed with the Commission on June 18, 2018 (the "IPO"). The Series A had no expiration date. ( 2 )The reported securities are beneficially owned by Omega Fund IV GP, L.P. ("Omega IV GP"), as the general partner of Omega Fund IV, L.P. ("Omega IV"). Omega Fund IV G.P. Manager, Ltd. ("Omega IV GP Manager"), is the general partner of Omega IV GP. Otello Stampacchia, Richard Lim and Anne-Mari Paster are all the shareholders and directors of Omega IV GP Manager and have shared voting and investment power over the shares held by Omega Fund IV, L.P. Each of the Reporting Persons disclaims beneficial ownership of these securities, except to the extent of his, her or its pecuniary interest therein. ( 3 )The Series B Redeemable Convertible Preferred Stock ("Series B") converted automatically into shares of the issuer's common stock on a one-for-one basis upon the completion of the IPO. The Series B had no expiration date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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