Sec Form 4 Filing - HAN QUEENA @ XBiotech Inc. - 2020-08-24

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person HAN QUEENA 2. Issuer Name and Ticker or Trading Symbol XBiotech Inc. [ XBIT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) VP Finance & HR (Last) (First) (Middle) 5217 WINNEBAGO LANE 3. Date of Earliest Transaction (MM/DD/YY) 08/24/2020 (Street) AUSTIN, TX78744 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 08/24/2020 M 18,700 A $ 7.5 18,700 D Common Shares 08/24/2020 S 18,700 D $ 19.6543 0 D Common Shares 08/24/2020 M 5,000 A $ 15 5,000 D Common Shares 08/24/2020 S 5,000 D $ 19.6543 0 D Common Shares 08/24/2020 M 12,308 A $ 4.16 12,308 D Common Shares 08/24/2020 S 12,308 D $ 19.6543 0 D Common Shares 08/24/2020 M 3,333 A $ 4.14 3,333 D Common Shares 08/24/2020 S 3,333 D $ 19.6543 0 D Common Shares 08/24/2020 M 12,500 A $ 5.26 12,500 D Common Shares 08/24/2020 S 12,500 D $ 19.6543 0 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock options $ 7.5 08/24/2020 M 18,700 02/28/2012 02/28/2021 Common Stocks 18,700 $ 0 0 D Stock Options $ 15 08/24/2020 M 5,000 12/12/2013 12/12/2022 Common Stocks 5,000 $ 0 0 D Stock Options $ 4.16 08/24/2020 M 12,308 05/08/2019 05/08/2028 Common Stocks 12,308 $ 0 0 D Stock Options $ 4.14 08/24/2020 M 3,333 12/07/2019 12/07/2028 Common Stocks 3,333 $ 0 0 D Stock Options $ 5.26 08/24/2020 M 12,500 01/04/2020 01/04/2029 Common Stocks 12,500 $ 0 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other HAN QUEENA 5217 WINNEBAGO LANE AUSTIN, TX78744 VP Finance & HR Signatures /S/ Queena Han 08/26/2020 Signature of Reporting Person Date

Explanation of Responses:

Remarks: The Reporting Person has placed a cashless sale for Non Qualified Stock Options on August 17, 2020 and sold 51,841 shares of common stock underlying these options on Aug 24, 2020.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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