Sec Form 5 Filing - Emerald Health Sciences Inc. @ Skye Bioscience, Inc. - 2021-12-31-05:00

FORM 5 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Emerald Health Sciences Inc. 2. Issuer Name and Ticker or Trading Symbol Skye Bioscience, Inc. [ SKYE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) OFFICE 8262, THE LANDING, 200-375 WATER ST. 3. Date of Earliest Transaction (MM/DD/YY) 12/31-05:00/2021 (Street) VANCOUVER, A1V6B 0M9 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 08/07-05:00/2020 S( 1 ) V 2,566,666 D $ 0.1 111,387,251 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Warrants with Credit Facility of Oct 5, 2018 $ 0.5 11/01-05:00/2018 A( 1 ) V 2,500,000 11/01-05:00/2018 11/01-05:00/2023 Common Stock 2,500,000 $ 0 2,500,000 D Warrants with Credit Facility of Oct 5, 2018 $ 0.5 02/01-05:00/2019 A( 1 ) V 2,500,000 02/01-05:00/2019 02/01-05:00/2024 Common Stock 2,500,000 $ 0 2,500,000 D Warrants with Credit Facility of Oct 5, 2018 $ 0.5 03/29-05:00/2019 A( 1 ) V 2,500,000 03/29-05:00/2019 03/29-05:00/2024 Common Stock 2,500,000 $ 0 2,500,000 D Multi Draw Credit Facility - T2 $ 0.4 02/01-05:00/2019 A( 1 ) V 38,822 10/05-05:00/2022 10/05-05:00/2022( 2 ) Common Stock 38,822 $ 0 38,822 D Multi Draw Credit Facility - T3 $ 0.4 03/29-05:00/2019 A( 1 ) V 5,354,861 10/05-05:00/2022 10/05-05:00/2022( 2 ) Common Stock 5,354,861 $ 0 5,354,861 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Emerald Health Sciences Inc. OFFICE 8262 THE LANDING, 200-375 WATER ST. VANCOUVER, A1V6B 0M9 X Signatures /s/ Stephen Hall 01/31-05:00/2022 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Transactions were previously reported on various prior Form 4 filings; however, the entries were erroneously reported as non-derivative transactions in Common Stock and the resulting reported total ownership included the misclassified securities. The entry of these transactions is to correct this error and reflect the actual securities held by the Reporting Person. ( 2 )The Multi Draw Credit Facility tranches have the option to convert into Common Stock upon maturity of the facilities.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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