Sec Form 4 Filing - Bultot Hugues @ Orgenesis Inc. - 2015-06-18

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Bultot Hugues 2. Issuer Name and Ticker or Trading Symbol Orgenesis Inc. [ ORGS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) AVENUE DE L'HORIZON 24 3. Date of Earliest Transaction (MM/DD/YY) 06/18/2015 (Street) WOLUWE SAINT PIERRE, C91150 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares ( 6 ) 5,050,454 D Common Shares ( 6 ) 01/16/2017 J( 1 ) 376,115 D 4,674,339 D Common Shares ( 6 ) 11/17/2017 X( 4 ) 2,452,751 A $ 356,549.04 7,127,090 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Options ( 6 ) ( 3 ) 03/02/2015 11/05/2017 Common Stock 2,650,108 2,650,108 D Stock Options ( 6 ) ( 3 ) 01/16/2017 J( 2 ) 197,357 03/02/2015 11/05/2017 Common Stock 197,357 ( 2 ) 2,452,751 D Stock Options ( 6 ) $ 0.1454 11/17/2017 X 2,452,751 03/02/2015 11/05/2017 Common Stock 2,452,751 ( 4 ) 0 D Stock Options ( 6 ) $ 0.53 06/18/2015 A 250,000 06/18/2015 06/18/2020 Common Stock 250,000 $ 0.53 250,000 D Stock Options ( 6 ) $ 0.4 12/09/2016 A 500,000 ( 5 ) 12/09/2026 Common Stock 500,000 $ 0.4 750,000 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Bultot Hugues AVENUE DE L'HORIZON 24 WOLUWE SAINT PIERRE, C91150 X Signatures /s/ Hugues Bultot 12/06/2017 Signature of Reporting Person Date

Explanation of Responses:

( 1 )As a result of the termination of the Masthercell SA's convertible note without conversion, the number of shares of common stock of Orgenesis Inc. (the "Issuer") received by Mr. Hugues Bultot as consideration for the purchase of Masthercell SA by the Issuer was reduced by 376,115 shares. ( 2 )Under a private agreement Mr. Hugues Bultot had an option to purchase 2,650,108 shares of common stock of the Issuer from the Universite Libre de Bruxelles.As a result of the termination of the Masthercell SA's convertible note without conversion, the number of shares purchasable under the option was reduced by 197,357 shares. ( 3 )The price per share was to be calculated on the basis of the total price for all shares taking into account the following formula: Total price for all shares = 750,000 EUR * (1 + 12.5%)N whereby N = the number of years after October 14, 2011, it being understood that in case the option is exercised before November 5, 2015 this number of years is increased by one. ( 4 )On November 17, 2017, Mr. Bultot exercised the option to purchase 2,452,751 shares at an exercise price of $0.1454 per share from the Universite Libre de Bruxelles. ( 5 )Vest quarterly over two years. ( 6 )The information in this Form 4 does not reflect a reverse stock split of the Issuer's common stock at a ratio of 1-for-12, effective as of November 13, 2017.

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* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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