Sec Form 4 Filing - TULLIS JAMES L L @ Alphatec Holdings, Inc. - 2022-04-07

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL OMB Number: 3235-0287 Expires: November 30, 2011 Estimated average burden hours per response... 0.5

1. Name and Address of Reporting Person TULLIS JAMES L L 2. Issuer Name and Ticker or Trading Symbol Alphatec Holdings, Inc. [ ATEC] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O ALPHATEC SPINE, INC., 1950 CAMINO VIDA ROBLE 3. Date of Earliest Transaction (MM/DD/YY) 04/07/2022 (Street) CARLSBAD, CA92008 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/07/2022 X 6,052 A $ 3.5 163,142 D Common Stock 04/07/2022 S( 1 ) 1,630 D $ 12.99 161,512 D Common Stock 04/07/2022 X 105,708 A $ 3.5 576,455 I By Tullis Growth Fund, L.P. Common Stock 04/07/2022 S( 2 ) 28,481 D $ 12.99 547,974 I By Tullis Growth Fund, L.P. Common Stock 04/07/2022 X 145,522 A $ 3.5 1,036,815 I By Tullis Dickerson Capital Focus III, LP Common Stock 04/07/2022 S( 3 ) 39,209 D $ 12.99 997,606 I By Tullis Dickerson Capital Focus III, LP Common Stock 248,225 I By Tullis-Dickerson Partners III, LLC

Table II - Deriv ative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Warrants (right to buy) $ 3.5 04/07/2022 X 6,052 ( 4 ) ( 4 ) Common Stock 6,052 $ 0 12,286 D Warrants (right to buy) $ 3.5 04/07/2022 X 105,708 ( 4 ) ( 4 ) Common Stock 105,708 $ 0 214,618 I By Tullis Growth Fund, L.P. Warrants (right to buy) $ 3.5 04/07/2022 X 145,522 ( 4 ) ( 4 ) Common Stock 145,522 $ 0 295,451 I By Tullis Dickerson Capital Focus III, LP

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other TULLIS JAMES L L C/O ALPHATEC SPINE, INC. 1950 CAMINO VIDA ROBLE CARLSBAD, CA92008 X Signatures /s/ James L.L. Tullis 04/11/2022 Signature of Reporting Person Date

Explanation of Responses:

( 1 )On April 7, 2022, the reporting person exercised warrants to purchase 6,052 shares of the issuer's common stock for $3.50 per share. The reporting person paid the exercise price on a cashless basis, resulting in the issuer withholding 1,630 of the warrant shares to pay the exercise price and issuing to the reporting person 4,422 shares. ( 2 )On April 7, 2022, Tullis Growth Fund, L.P. exercised warrants to purchase 105,708 shares of the issuer's common stock for $3.50 per share. Tullis Growth Fund, L.P. paid the exercise price on a cashless basis, resulting in the issuer withholding 28,481 of the warrant shares to pay the exercise price and issuing to Tullis Growth Fund, L.P. 77,227 shares. ( 3 )On April 7, 2022, Tullis Dickerson Capital Focus III, LP exercised warrants to purchase 145,522 shares of the issuer's common stock for $3.50 per share. Tullis Dickerson Capital Focus III, LP paid the exercise price on a cashless basis, resulting in the issuer withholding 39,209 of the warrant shares to pay the exercise price and issuing to Tullis Dickerson Capital Focus III, LP 106,313 shares. ( 4 )Each Warrant is exercisable for one share of the issuer's common stock for a period of five years following the date that stockholder approval of the issuance of the Warrants was obtained. The stockholders approved such issuance on May 17, 2018.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.