Sec Form 3 Filing - Blackburn Stan @ aTYR PHARMA INC - 2018-03-20

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Blackburn Stan 2. Issuer Name and Ticker or Trading Symbol aTYR PHARMA INC [ LIFE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner _____ Officer (give title below) X __ Other (specify below) See Remarks (Last) (First) (Middle) 3545 JOHN HOPKINS COURT, SUITE 250 3. Date of Earliest Transaction (MM/DD/YY) 03/20/2018 (Street) SAN DIEGO, CA92121 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 11,954 I By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 ( 1 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (right to buy) $ 0.72 ( 2 )( 3 ) 06/02/2021 Common Stock 129 D Stock Option (right to buy) $ 0.88 ( 2 )( 3 ) 09/13/2022 Common Stock 878 D Stock Option (right to buy) $ 4.06 ( 2 )( 3 ) 09/26/2023 Common Stock 2,514 D Stock Option (right to buy) $ 4.06 ( 2 )( 3 ) 03/05/2024 Common Stock 1,760 D Stock Option (right to buy) $ 9.15 ( 2 )( 4 ) 04/17/2025 Common Stock 3,143 D Stock Option (right to buy) $ 14 ( 2 )( 5 ) 05/06/2025 Common Stock 4,085 D Stock Option (right to buy) $ 10.24 ( 2 )( 6 ) 10/01/2025 Common Stock 9,500 D Stock Option (right to buy) $ 6.14 ( 2 )( 7 ) 01/27/2026 Common Stock 4,250 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Blackburn Stan 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO, CA92121 See Remarks Signatures Nancy D. Krueger, Attorney-In-Fact 05/02/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The Reporting Person is a co-trustee of the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001. ( 2 )All options reported on this Form 3 were granted prior to February 2016 when the Reporting Person was a consultant, serving as the Company's Acting Chief Financial Officer. On March 20, 2018, the Reporting Person became the Company's Principal Financial and Accounting Officer. ( 3 )This option was fully vested and exercisable at the reporting date. ( 4 )The shares subject to this option vest in 48 equal monthly installments starting on May 17, 2015 and will be fully exercisable on April 17, 2019. This option is subject to accelerated vesting upon termination without cause upon a change in control of the Issuer. ( 5 )The shares subject to this option vest in 48 equal monthly installments starting on June 6, 2015 and will be fully exercisable on May 6, 2019. This option is subject to accelerated vesting upon termination without cause upon a change in control of the Issuer. ( 6 )The shares subject to this option vest in 48 equal monthly installments starting on November 1, 2015 and will be fully exercisable on October 1, 2019. This option is subject to accelerated vesting upon termination without cause upon a change in control of the Issuer. ( 7 )The shares subject to this option vest in 48 equal monthly installments starting on February 1, 2016 and will be fully exercisable on January 1, 2020. This option is subject to accelerated vesting upon termination without cause upon a change in control of the Issuer.

Remarks: Principal Financial and Accounting Officer

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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