Sec Form 4 Filing - MISSLING CHRISTOPHER U @ ANAVEX LIFE SCIENCES CORP. - 2016-07-05

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person MISSLING CHRISTOPHER U 2. Issuer Name and Ticker or Trading Symbol ANAVEX LIFE SCIENCES CORP. [ AVXL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) President, CEO & Treasurer (Last) (First) (Middle) 51 W 52ND STREET, 7TH FLOOR 3. Date of Earliest Transaction (MM/DD/YY) 07/05/2016 (Street) NEW YORK, NY10019-6163 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 6.26 07/05/2016 A 379,625 ( 1 ) 07/05/2026 Common Stock 379,625 $ 0 379,625 D Stock Option (Right to Buy) $ 7.06 07/18/2016 A 861,429 ( 2 ) 07/18/2026 Common Stock 861,429 $ 0 861,429 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other MISSLING CHRISTOPHER U 51 W 52ND STREET 7TH FLOOR NEW YORK, NY10019-6163 X President, CEO & Treasurer Signatures /s/ Christopher Missling, PhD 07/19/2016 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Pursuant to a First Amendment to the Employment Agreement between the Issuer and Dr. Christopher Missling (the "First Amendment") filed with the Securities and Exchange Commission on July 7, 2016, the Issuer issued to Dr. Missling options to purchase 379,625 shares of the Issuer's common stock with a grant date value of $2,000,000 as determined based on a Black Scholes formula, with such options to vest quarterly over a three-year period commencing on October 5, 2016. ( 2 )The Issuer amended the First Amendment to clarify the Board of Director's intention with respect to Dr. Missling's stock option grant and in connection therewith, the Issuer issued to Dr. Missling options to purchase 861,429 shares of the Issuer's common stock, with such options to vest quarterly over a three-year period commencing on October 18, 2016.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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