Sec Form 4 Filing - Durrant Cameron @ HUMANIGEN, INC - 2019-04-23

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Durrant Cameron 2. Issuer Name and Ticker or Trading Symbol HUMANIGEN, INC [ HGEN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O HUMANIGEN, INC., 533 AIRPORT BOULEVARD, SUITE 400 3. Date of Earliest Transaction (MM/DD/YY) 04/23/2019 (Street) BURLINGAME, CA94010 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, $0.001 par value 04/23/2019 A 75,000 A $ 0.665 313,583 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Employee Stock Option Exercise (Right to Buy) $ 0.665 04/23/2019 M 75,000 03/09/2018( 1 ) 09/12/2026 Common Stock 75,000 $ 0 8,359,771 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Durrant Cameron C/O HUMANIGEN, INC. 533 AIRPORT BOULEVARD, SUITE 400 BURLINGAME, CA94010 X Chief Executive Officer Signatures /s/ Deborah Brown, Attorney-In-Fact 04/25/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )These stock options were granted to the executive on March 9, 2018 to preserve the incentive offered to the executive in connection with his stock option granted on September 13, 2016, after giving effect to the dilution resulting from the completion of the Company's previously reported restructuring transaction on February 27, 2018. Accordingly, the option was deemed vested as to one-half of the underlying shares as of the grant date, with the remainder vesting in six quarterly installments commencing June 13, 2018.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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