Sec Form 4 Filing - Garden State Life Sciences Venture Fund L P @ AMICUS THERAPEUTICS INC - 2007-06-05

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Garden State Life Sciences Venture Fund L P 2. Issuer Name and Ticker or Trading Symbol AMICUS THERAPEUTICS INC [ FOLD] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O QUAKER BIOVENTURES, 2929 ARCH STREET, CIRA CENTRE 3. Date of Earliest Transaction (MM/DD/YY) 06/05/2007 (Street) PHILADELPHIA, PA19104 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 06/05/2007 C 1,064,822 A 1,064,822 I By Quaker BioVentures, L.P. ( 2 ) Common Stock 06/05/2007 C 354,940 A 1,419,762 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series C Convertible Preferred Stock ( 1 ) 06/05/2007 C 396,825 08/16/2005 ( 1 ) Common Stock 396,825 $ 0 0 I By Quaker Bioventures, L.P. ( 2 ) Series C Convertible Preferred Stock ( 1 ) 06/05/2007 C 132,275 08/16/2005 ( 1 ) Common Stock 132,275 $ 0 0 D Series C Convertible Preferred Stock ( 1 ) 06/05/2007 C 396,825 04/17/2006 ( 1 ) Common Stock 396,825 $ 0 0 I By Quaker Bioventures, L.P. ( 2 ) Series C Convertible Preferred Stock ( 1 ) 06/05/2007 C 132,275 04/17/2006 ( 1 ) Common Stock 132,275 $ 0 0 D Series D Convertible Preferred Stock ( 1 ) 06/05/2007 C 135,586 09/13/2006 ( 1 ) Common Stock 135,586 $ 0 0 I By Quaker Bioventures, L.P. ( 2 ) Series D Convertible Preferred Stock ( 1 ) 06/05/2007 C 45,195 09/13/2006 ( 1 ) Common Stock 45,195 $ 0 0 D Series D Convertible Preferred Stock ( 1 ) 06/05/2007 C 135,586 03/09/2007 ( 1 ) Common Stock 135,586 $ 0 0 I By Quaker Bioventures, L.P. ( 2 ) Series D Convertible Preferred Stock ( 1 ) 06/05/2007 C 45,195 03/09/2007 ( 1 ) Common Stock 45,195 $ 0 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Garden State Life Sciences Venture Fund L P C/O QUAKER BIOVENTURES 2929 ARCH STREET, CIRA CENTRE PHILADELPHIA, PA19104 X Signatures Garden State Life Sciences Venture Fund, L.P., By: Quaker BioVentures Capital, L.P., its General Partner, By: Quaker BioVentures Capital LLC, its General Partner, By: /s/ Richard S. Kollender 06/06/2007 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Each of the Series C Convertible Preferred Stock and Series D Convertible Preferred Stock automatically converted into Amicus Therapeutics, Inc. common stock on a one for one basis upon the closing of Amicus Therapeutics, Inc's initial public offering on June 5, 2007. ( 2 )These shares are owned by Quaker BioVentures, L.P., which is under common control with Garden State Life Sciences Venture Fund L.P. Quaker BioVentures Capital, L.P. serves as the general partner of Quaker BioVentures, L.P. and Garden State Life Sciences Venture Fund L.P. and is the indirect beneficial owner of these shares. Quaker Bioventures Capital LLC serves as the general partner of Quaker Bioventures Capital, L.P. and is also an indirect beneficial owner of these shares. Garden State Life Sciences Venture Fund L.P. disclaims beneficial ownership of these shares except to the extent of its proportionate pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purposes of section 16 of for any other purpose.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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