Sec Form 4 Filing - 1837 RMB Managers L.L.C. @ AspenBio Pharma, Inc. - 2007-07-18

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person 1837 RMB Managers L.L.C. 2. Issuer Name and Ticker or Trading Symbol AspenBio Pharma, Inc. [ apnb] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O RMB CAPITAL MANAGEMENT, LLC, 10 S. WACKER DR. STE 3210 3. Date of Earliest Transaction (MM/DD/YY) 07/18/2007 (Street) CHICAGO, IL60606 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price AspenBio Pharma, Inc. 07/18/2007 S 25,140 ( 2 ) D $ 5.43 2,775,271 ( 1 ) D AspenBio Pharma, Inc. 07/18/2007 S 6,030 ( 3 ) D $ 5.43 2,769,241 ( 1 ) D AspenBio Pharma, Inc. 07/18/2007 S 6,330 ( 4 ) D $ 5.43 2,762,911 ( 1 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other 1837 RMB Managers L.L.C. C/O RMB CAPITAL MANAGEMENT, LLC 10 S. WACKER DR. STE 3210 CHICAGO, IL60606 X 1837 Partners L.P. C/O RMB CAPITAL MANAGEMENT, LLC 10 S. WACKER DR. STE 3210 CHICAGO, IL60606 X 1837 Partners QP L.P. C/O RMB CAPITAL MANAGEMENT, LLC 10 S. WACKER DR. STE. 3210 CHICAGO, IL60606 X 1837 Partners Ltd. C/O RMB CAPITAL MANAGEMENT, LLC 10 S. WACKER DRIVE, STE. 3210 CHICAGO, IL60606 X Signatures Richard M. Burridge, Jr. 07/18/2007 Signature of Reporting Person Date

Explanation of Responses:

( 1 )These securities are directly owned by 1837 Partners L.P., 1837 Partners QP L.P., 1837 Partners Ltd. ("Partnerships"). As the General Partner to the Partnerships, 1837 RMB Managers LLC, may be deemed as the beneficial owner of the Issuer's securities held by the Partnerships. 1837 RMB Managers LLC, disclaims any beneficial ownership of any of the Issuer's securities reported herein for the purposes of Rule 16a-1 under the Securities Exchange Act of 1934, as amended, or otherwise, except as to the securities representing 1837 RMB Managers LLC's pro rata interest in the profits of the Partnerships. ( 2 )These shares were sold by 1837 Partners L.P. ( 3 )These shares were sold from 1837 Partners QP L.P. ( 4 )These shares were sold from 1837 Partners Ltd.

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