Sec Form 3 Filing - Mattacchione Robert @ Novo Integrated Sciences, Inc. - 2021-02-19

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Mattacchione Robert 2. Issuer Name and Ticker or Trading Symbol Novo Integrated Sciences, Inc. [ NVOS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O NOVO INTEGRATED SCIENCE INC., 11120 NE 2ND ST, SUITE 100 3. Date of Earliest Transaction (MM/DD/YY) 02/19/2021 (Street) BELLEVUE, WA98004 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock ( 1 ) 12,908,562 I See Footnote ( 2 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (right to buy) ( 1 ) ( 3 ) $ 1.6 05/03/2017 05/03/2024 Common Stock 25,000 I By spouse

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Mattacchione Robert C/O NOVO INTEGRATED SCIENCE INC. 11120 NE 2ND ST, SUITE 100 BELLEVUE, WA98004 X X Chief Executive Officer Signatures /s/ Christopher David, as Attorney -in- Fact for Robert Mattachione 02/19/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Information reported on this Form 3 has been adjusted to give effect to the 1-for-10 reverse stock split of the issuer's common stock, which was effective on February 1, 2021. ( 2 )Shares are owned by ALMC-ASAP Holdings, Inc., which is wholly owned by the Mattacchione Family Trust. The reporting person is trustee of the Mattacchione Family Trust, with voting and dispositive power over the shares. ( 3 )Represents a grant by the issuer, approved by the issuer's Board of Directors.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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