Sec Form 4 Filing - NOHRA GUY P @ FLAMEL TECHNOLOGIES SA - 2003-10-02

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL OMB Number: 3235-0287 Expires: November 30, 2011 Estimated average burden hours per response... 0.5

1. Name and Address of Reporting Person NOHRA GUY P 2. Issuer Name and Ticker or Trading Symbol FLAMEL TECHNOLOGIES SA [ FLML] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner _____ Officer (give title below) X __ Other (specify below) See Footnotes (Last) (First) (Middle) ONE EMBARCADERO CENTER, SUITE 4050 3. Date of Earliest Transaction (MM/DD/YY) 10/02/2003 (Street) SAN FRANCISCO, CA94111 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 10/02/2003 D 1,181,017 D $ 33.25 170,937 I See Footnote 1( 1 ) Common Stock 10/02/2003 D 674,468 D $ 33.25 97,620 I See Footnote 2( 2 ) Common Stock 10/02/2003 D 44,515 D $ 33.25 6,443 I See Footnote 3( 3 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other NOHRA GUY P ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO, CA94111 See Footnotes Signatures Guy Nohra 10/03/2003 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Alta BioPharma L.P. ("Alta BioP") converted its common stock into ADS pursuant to Flamel Technologies Form F-3 Reg#333-108-202. Alta Partners directly or indirectly provides investment advisory services to various venture capital funds, including Alta BioP. The General Partner of Alta BioP exercises sole voting and investment power with respect to the shares held by the fund. The principals of Alta Partners are Jean Deleage, Guy Nohra, Garrett Gruener, Daniel Janney, Alix Marduel (collectively known as the "principals"). Certain principals of Alta Partners are managing directors of Alta BioPharma Mgt, LLC (the GP of Alta BioP), as managing directors they may be deemed to share voting and investment powers of the shares held by the funds. These principals disclaim beneficial ownership, except to the extent of their proportionate interests therein. X\Ref to Form 4 filed for Alta Partners on 10/3/03. ( 2 )Flamel Chase Partners (AltaBio),LLC ("Flamel Chase") converted its common stock into ADS pursuant to Flamel Technologies Form F-3 Reg#333-108-202. Alta Partners directly or indirectly provides investment advisory services to various venture capital funds, including Flamel Chase. The managing member of Flamel Chase exercises sole voting and investment power with respect to the shares held by the fund. The principals of Alta Partners are Jean Deleage, Guy Nohra, Garrett Gruener, Daniel Janney, Alix Marduel (collectively known as the "principals"). Certain principals of Alta Partners are members of Alta/Chase BioPharma Management, LLC (the managing member of Flamel Chase), as members they may be deemed to share voting and investment powers of the shares held by the funds. These principals disclaim beneficial ownership of all such shares, except to the extent of their proportionate interests therein. X\ref to Form 4 for Alta Partners filed on 10/3/03. ( 3 )Alta Embarcadero BioPharma Partners,LLC ("Alta Embarcadero") converted its common stock into ADS pursuant to Flamel Technologies Form F-3 Reg#333-108-202. Alta Partners directly or indirectly provides investment advisory services to various venture capital funds, including Alta Embarcadero. The members of Alta Embarcadero exercises sole voting and investment power with respect to the shares held by the fund. The principals of Alta Partners are Jean Deleage, Guy Nohra, Garrett Gruener, Daniel Janney, Alix Marduel (collectively known as the "principals"). Certain principals of Alta Partners are members of Alta Embarcadero, as members they may be deemed to share voting and investment powers of the shares held by the funds. These principals disclaim beneficial ownership of all such shares, except to the extent of their proportionate interests therein. X\ref to Form 4 for Alta Partners filed on 10/3/03.

Remarks: This form 4 is part 2 of a group filing. Part one is filed under the reporting name of Alta Partners, the entity that is the beneficial owners of the shares. It was filed on 10/3/03.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.