Sec Form 4 Filing - MCNEILL JOHN A JR @ PHARMACEUTICAL PRODUCT DEVELOPMENT INC - 2011-02-24

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person MCNEILL JOHN A JR 2. Issuer Name and Ticker or Trading Symbol PHARMACEUTICAL PRODUCT DEVELOPMENT INC [ PPDI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 304 EAST OLIVER STREET 3. Date of Earliest Transaction (MM/DD/YY) 02/24/2011 (Street) WHITEVILLE, NC28472 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/24/2011 M 8,281 A $ 15.28 89,148 D Common Stock 2,613,942 I Trust Common Stock 365,485 I Limited Partnership Common Stock 1,195 I LLC

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Options (to buy) $ 15.28 02/24/2011 M 8,281 05/15/2001 05/14/2011 Common Stock 8,281 $ 0 0 D Stock Options (to buy) $ 24.26 07/30/2011( 1 ) 07/30/2020 Common Stock 9,090 9,090 D Stock Options (to buy) $ 24.52 05/20/2010 05/20/2020 Common Stock 10,496 10,496 D Stock Options (to buy) $ 19.19 05/20/2009 05/20/2019 Common Stock 14,053 14,053 D Stock Options (to buy) $ 41.32 05/21/2008 05/20/2018 Common Stock 6,485 6,485 D Stock Options (to buy) $ 12.37 05/15/2002 05/14/2012 Common Stock 12,421 12,421 D Stock Options (to buy) $ 13.12 05/14/2003 05/13/2013 Common Stock 16,561 16,561 D Stock Options (to buy) $ 14.55 05/19/2004 05/18/2014 Common Stock 16,561 16,561 D Stock Options (to buy) $ 22.98 05/18/2005 05/17/2015 Common Stock 5,650 5,650 D Stock Options (to buy) $ 34.18 05/17/2006 05/16/2016 Common Stock 4,113 4,113 D Stock Options (to buy) $ 32.67 05/16/2007 05/15/2017 Common Stock 6,341 6,341 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other MCNEILL JOHN A JR 304 EAST OLIVER STREET WHITEVILLE, NC28472 X Signatures Lisa C. Noecker attorney-in-fact for John A. McNeill, Jr. 02/25/2011 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The options vest in three equal increments on 7/30/2011, 7/30/2012 and 7/30/2013.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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