Sec Form 13G Filing - PRINCIPAL GLOBAL INVESTORS filing for CASTLE BIOSCIENCES INC (CSTL) - 2024-02-13

Insider filing report for Changes in Beneficial Ownership

  • Schedule 13G & 13D forms are used to report a party's ownership of stock which exceeds 5% of a company's total stock issue.
  • Schedule 13G is a shorter version of Schedule 13D with fewer reporting requirements.
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240.13d-102 Schedule 13G - Information to be included in statements
filed pursuant to 240.13d-1(b), (c), and (d) and amendments thereto
filed pursuant to 240.13d-2.

Securities and Exchange Commission, Washington, D.C. 20549
Schedule 13G
Under the Securities Exchange Act of 1934
(Amendment No. __)
(Name of Issuer)
CASTLE BIOSCIENCES INC
(Title of Class of Securities)
Common Stock, $0.001 par value per share

(CUSIP Number)

14843C105

(Date of Event Which Requires Filing of this Statement)
December 31,2023

Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:

[X ] Rule 13d-1(b)
[  ] Rule 13d-1(c)
[  ] Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject to the
liabilities of that section of the Act but shall be subject to all
other provisions of the Act (however, see the Notes).



CUSIP No. 14843C105
(1) Names of reporting persons    Principal Global Investors, LLC

(2) Check the appropriate box if a member of a group
(a)
		(see instructions)
(b)
(3) SEC use only

(4) Citizenship or place of organization: Delaware

Number of shares beneficially owned by each reporting person with:

(5) Sole voting power                  0

(6) Shared voting power              1,585,639 (see Item 4)

(7) Sole dispositive power           0

(8) Shared dispositive power       1,585,639 (see Item 4)

(9) Aggregate amount beneficially owned by each reporting person
1,585,639 (see Item 4)

(10) Check if the aggregate amount in Row (9) excludes certain
shares
(see instructions)

(11) Percent of class represented by amount in Row (9) 5.89 (see
Item 4)

(12) Type of reporting person (see instructions)     IA


Item 1(a) Name of issuer:
CASTLE BIOSCIENCES INC
Item 1(b) Address of issuer's principal executive offices:
505 S FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD, TX, 77546
2(a) Name of person filing:
This statement is filed by: (i) Principal Global Investors, LLC.

2(b) Address or principal business office or, if none, residence:

Principal Global Investors, LLC
801 Grand Avenue
Des Moines, IA 50392.
2(c) Citizenship:
Principal Global Investors, LLC - State of Delaware
2(d) Title of class of securities:
Common Stock, $0.001 par value per share
2(e) CUSIP Number:
14843C105

Item 3.

(e) [X] An investment adviser in accordance with
	section 240.13d1(b)(1)(ii)(E)

Item 4. Ownership

As of the close of business on December 31,2023:

1. Principal Global Investors, LLC
(a) Amount beneficially owned: 1,585,639
(b) Percent of class: 5.89
(c) Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote: 0
(ii) Shared power to vote or to direct the vote: 1,585,639
(iii) Sole power to dispose or to direct the disposition of: 0

(iv) Shared power to dispose or to direct the disposition of:
1,585,639

Item 5: Ownership of 5 Percent or Less of a Class.

If this statement is being filed to report the fact that as of the
date hereof the reporting person has ceased to be the beneficial owner
of more than 5 percent of the class of securities, check the following
[].

Instruction. Dissolution of a group requires a response to this item.
Item 6.  Ownership of More than 5 Percent on Behalf of Another Person.

Not applicable

Item 7.  Identification and Classification of the Subsidiary Which
Acquired the Security Being Reporting on by the Parent Holding Company
or Control Person.

Not applicable

Item 8. Identification and Classification of Members of the Group

Not applicable

Item 9.  Notice of Dissolution of Group.

Not applicable

Item 10. Certifications

By signing below, I certify that, to the best of his/her knowledge and
belief, the securities referred to above were not acquired and are not
held for the purpose of or with the effect of changing or influencing
the control of the issuer of the securities and were not acquired and
are not held in connection with or as a participant in any transaction
having that purpose or effect.

Signature.  After reasonable inquiry and to the best of my knowledge
and belief, I certify that the information set forth in this statement
is true, complete, and correct.

Dated: February 9, 2024
Principal Global Investors, LLC
By:

/s/ Jill Hittner
Name: Jill Hittner
Title: Chief Financial Officer