Sec Form 13G Filing - Capital regional et cooperatif Desjardins filing for Ocera Therapeutics Inc. (OCRX) - 2012-02-14

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

o

Rule 13d-1(b)

o

Rule 13d-1(c)

x

Rule 13d-1(d)

CUSIP No. 89413J102

1.

Names of Reporting Persons
Capital regional et cooperative Desjardins (CRCD)

I.R.S. Identification Nos. of above persons (entities only).

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

x (1)

(b)

o

3.

SEC Use Only

4.

Citizenship or Place of Organization
Québec, Canada

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

5.

Sole Voting Power
1,232,301

6.

Shared Voting Power
29,721

7.

Sole Dispositive Power
1,232,301

8.

Shared Dispositive Power
29,721

9.

Aggregate Amount Beneficially Owned by Each Reporting Person
1,262,022 (2)

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  o

11.

Percent of Class Represented by Amount in Row (9)
5.1% (3)

12.

Type of Reporting Person (See Instructions)
CO

CUSIP No. 89413J102

1.

Names of Reporting Persons
Desjardins-Innovatech S.E.C.

I.R.S. Identification Nos. of above persons (entities only).

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

x (1)

(b)

o

3.

SEC Use Only

4.

Citizenship or Place of Organization
Québec, Canada

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

5.

Sole Voting Power
0

6.

Shared Voting Power
29,721

7.

Sole Dispositive Power
0

8.

Shared Dispositive Power
29,721

9.

Aggregate Amount Beneficially Owned by Each Reporting Person
29,721

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  o

11.

Percent of Class Represented by Amount in Row (9)
0.1% (2)

12.

Type of Reporting Person (See Instructions)
PN

Item 1.

(a)

Name of Issuer
Tranzyme, Inc. (the “Issuer”)

(b)

Address of Issuer’s Principal Executive Offices
4819 Emperor Boulevard, Ste. 400, Durham, North Carolina 27703, United States

Item 2.

(a)

Name of Person Filing
(1)  Capital regional et coopératif Desjardins

(2)  Desjardins-Innovatech S.E.C.

(b)

Address of Principal Business Office or, if none, Residence
2 Complexe Desjardins, #1717

P.O. Box 760

Montreal, Québec, Canada H5B 1B8

(c)

Citizenship
Each of the Capital regional et coopératif Desjardins and Desjardins-Innovatech S.E.C. is organized in Québec, Canada.

(d)

Title of Class of Securities
Common stock, $0.00001 par value per share (the “Common Stock”).

(e)

CUSIP Number
The CUSIP number of the Common Stock is 89413J102.

Item 3.

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

o

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);

(b)

o

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

(c)

o

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);

(d)

o

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e)

o

An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f)

o

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

(g)

o

A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G);

(h)

o

A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

o

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

o

A non-U.S. institution in accordance with § 240.13d–1(b)(1)(ii)(J);

(k)

o

Group, in accordance with § 240.13d–1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with

§ 240.13d–1(b)(1)(ii)(J), please specify the type of institution:____________________________

Not Applicable.

Item 4.

Ownership

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

(a) and (b)

Capital regional et cooperative Desjardins beneficially owns 1,262,022 shares of common stock, or 5.1% of the outstanding shares of common stock, which consists of (i) 1,232,301 shares of common stock held of record by Capital regional et cooperative Desjardins and (ii) 29,721 shares of common stock held of record by Desjardins-Innovatech S.E.C.  Desjardins-Innovatech S.E.C. beneficially owns 29,721 shares of common stock, or 0.1%

(c)

Capital regional et coopérative Desjardins has sole power to vote or to direct the vote of 1,232,301 shares of common stock, sole power to dispose or to direct the disposition of 1,232,301 shares of the common stock, shared power to vote or to direct the vote of 29,721 shares of the common stock and shared power to dispose or to direct the disposition of 29,721 shares of the common stock.

&# xA0;

Desjardins-Innovatech S.E.C. has sole power to vote or to direct the vote of no shares of common stock, sole power to dispose or to direct the disposition of no shares of the common stock, shared power to vote or to direct the vote of 29,721 shares of the common stock and shared power to dispose or to direct the disposition of 29,721 shares of the common stock.

Item 5.

Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following   o.

Item 6.

Ownership of More than Five Percent on Behalf of Another Person

Not Applicable.

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person

Not Applicable.

Item 8.

Identification and Classification of Members of the Group

Not Applicable.

Item 9.

Notice of Dissolution of Group

Not Applicable.

Item 10.

Certification

Not Applicable.

ATTENTION

Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).