Sec Form 13G Filing - BAKER BROS. ADVISORS LP filing for Mereo BioPharma Group plc (MREO) - 2023-08-10

Insider filing report for Changes in Beneficial Ownership

  • Schedule 13G & 13D forms are used to report a party's ownership of stock which exceeds 5% of a company's total stock issue.
  • Schedule 13G is a shorter version of Schedule 13D with fewer reporting requirements.
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SCHEDULE 13G

 

SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

 

Under the Securities Exchange Act of 1934
(Amendment No. 3)*

 

Mereo BioPharma Group plc

(Name of Issuer)

 

Ordinary Shares, nominal value £0.003 per share

(Title of Class of Securities)

 

589492107**

 

(CUSIP Number)

 

July 31, 2023

 
 

(Date of Event which Requires Filing of this Statement)

 

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

 

  x Rule 13d-1(b)

 

  ¨ Rule 13d-1(c)

 

  ¨ Rule 13d-1(d)

 

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (the “Act”) or otherwise subject to the liabilities of that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes).

 

**This CUSIP applies to the American Depositary Shares, each representing five Ordinary Shares

 

 

 

 

 CUSIP No.  589492107

 

1 NAMES OF REPORTING PERSONS

Baker Bros. Advisors LP
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b) ¨

3

SEC USE ONLY

 

4 CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

 

 

5

 

SOLE VOTING POWER

14,604,391 (1)
6 SHARED VOTING POWER

-0-
7 SOLE DISPOSITIVE POWER

14,604,391 (1)
8 SHARED DISPOSITIVE POWER

-0-

9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,604,391 (1)
10

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

(See Instructions)

 

¨
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

2.2% (1)(2)
12 TYPE OF REPORTING PERSON (See Instructions)

IA, PN
  (1) Includes 14,604,391 Ordinary Shares (“Ordinary Shares”) of Mereo BioPharma Group plc (the “Issuer”) represented by 2,920,878 American Depositary Shares (“ADS”) that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein), directly held by the Funds (as defined below i n Item 4). Each ADS represents 5 Ordinary Shares of the Issuer.
  (2) Based on 643,204,794 Ordinary Shares of the Issuer outstanding as of June 9, 2023, as obtained in an email received from the Issuer on July 25, 2023, plus 14,604,391 Ordinary Shares represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein) and 9,645,200 Ordinary Shares represented by 1,929,040 ADS issued in a conversion of Tranche 1 Notes by the Funds on July 21, 2023.
         

 

 CUSIP No.  589492107

 

1 NAMES OF REPORTING PERSONS

Baker Bros. Advisors (GP) LLC
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b) ¨

3

SEC USE ONLY

 

4 CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

 

 

5

 

SOLE VOTING POWER

14,604,391 (1)
6 SHARED VOTING POWER

-0-
7 SOLE DISPOSITIVE POWER

14,604,391 (1)
8 SHARED DISPOSITIVE POWER

-0-

9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,604,391 (1)
10

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

(See Instructions)

 

¨
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

2.2% (1)(2)
12 TYPE OF REPORTING PERSON (See Instructions)

HC, OO

 

  (1) Includes 14,604,391 Ordinary Shares of the Issuer represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein), directly held by the Funds (as defined below in Item 4). Each ADS represents 5 Ordinary Shares of the Issuer.

 

  (2) Based on 643,204,794 Ordinary Shares of the Issuer outstanding as of June 9, 2023, as obtained in an email received from the Issuer on July 25, 2023, plus 14,604,391 Ordinary Shares represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein) and 9,645,200 Ordinary Shares represented by 1,929,040 ADS issued in a conversion of Tranche 1 Notes by the Funds on July 21, 2023.

 

 

 CUSIP No.  589492107

 

1 NAMES OF REPORTING PERSONS

Felix J. Baker
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b) ¨

3

SEC USE ONLY

 

4 CITIZENSHIP OR PLACE OF ORGANIZATION

United States

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

 

 

5

 

SOLE VOTING POWER

14,604,391 (1)
6 SHARED VOTING POWER

-0-
7 SOLE DISPOSITIVE POWER

14,604,391 (1)
8 SHARED DISPOSITIVE POWER

-0-

9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,604,391 (1)
10

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

(See Instructions)

 

¨
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

2.2% (1)(2)
12 TYPE OF REPORTING PERSON (See Instructions)

IN, HC

 

  (1) Includes 14,604,391 Ordinary Shares of the Issuer represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein), directly held by the Funds (as defined below in Item 4). Each ADS represents 5 Ordinary Shares of the Issuer.

 

  (2) Based on 643,204,794 Ordinary Shares of the Issuer outstanding as of June 9, 2023, as obtained in an email received from the Issuer on July 25, 2023, plus 14,604,391 Ordinary Shares represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein) and 9,645,200 Ordinary Shares represented by 1,929,040 ADS issued in a conversion of Tranche 1 Notes by the Funds on July 21, 2023.

 

 

 CUSIP No.  589492107  

 

1 NAMES OF REPORTING PERSONS

Julian C. Baker
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b) ¨

3

SEC USE ONLY

 

4 CITIZENSHIP OR PLACE OF ORGANIZATION

United States

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

 

 

5

 

SOLE VOTING POWER

14,604,391 (1)
6 SHARED VOTING POWER

-0-
7 SOLE DISPOSITIVE POWER

14,604,391 (1)
8 SHARED DISPOSITIVE POWER

-0-

9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,604,391 (1)
10

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

(See Instructions)

 

¨
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

2.2% (1)(2)
12 TYPE OF REPORTING PERSON (See Instructions)

IN, HC

 

  (1) Includes 14,604,391 Ordinary Shares of the Issuer represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein), directly held by the Funds (as defined below in Item 4). Each ADS represents 5 Ordinary Shares of the Issuer.

 

  (2) Based on 643,204,794 Ordinary Shares of the Issuer outstanding as of June 9, 2023, as obtained in an email received from the Issuer on July 25, 2023, plus 14,604,391 Ordinary Shares represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes (as defined in Item 4 and subject to the limitations as described therein) and 9,645,200 Ordinary Shares represented by 1,929,040 ADS issued in a conversion of Tranche 1 Notes by the Funds on July 21, 2023.

 

 

Amendment No. 3 to Schedule 13G

 

This Amendment No. 3 to Schedule 13G amends and restates the previously filed Schedule 13G filed by Baker Bros. Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Julian C. Baker and Felix J. Baker (collectively, the “Reporting Persons”). Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect.

 

Item 1(a) Name of Issuer:

 

Mereo BioPharma Group plc (the “Issuer”)

 

Item 1(b) Address of Issuer’s Principal Executive Offices:

 

One Cavendish Place, 4th Floor

 

London, W1G 0QF United Kingdom

 

Item 2(a) Name of Person Filing:

 

This Amendment No. 3 is being filed jointly by the Reporting Persons.

 

Item 2(b) Address of Principal Business Office or, if None, Residence:

 

The business address of each of the Reporting Persons is:

 

c/o Baker Bros. Advisors LP

 

860 Washington Street, 3rd Floor

 

New York, NY 10014

 

(212) 339-5690

 

Item 2(c) Citizenship:

 

The Adviser is a limited partnership organized under the laws of the State of Delaware. The Adviser GP is a limited liability company organized under the laws of the State of Delaware. The citizenship of each of Julian C. Baker and Felix J. Baker is the United States of America.

 

Item 2(d) Title of Class of Securities:

 

Ordinary Shares, nominal value £0.003 per share (“Ordinary Shares”).

 

Item 2(e) CUSIP Number:

 

589492107

 

 

Item 3 If this statement is filed pursuant to §§240.13d-1(b) or (c), check whether the person filing is a:

 

  (a)  ¨ Broker or dealer registered under Section 15 of the Exchange Act.
   
  (b)  ¨ Bank as defined in section 3(a)(6) of the Exchange Act.
   
  (c)  ¨ Insurance company as defined in section 3(a)(19) of the Exchange Act.
   
  (d)  ¨ Investment company registered under section 8 of the Investment Company Act of 1940.
   
  (e)  x An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).
   
  (f)  ¨ An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).
   
  (g)  x A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).
   
  (h)  ¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act.
   
  (i)  ¨ A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940.
   
  (j)  ¨ Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

 

Item 4          Ownership:

 

Items 5 through 9 and 11 of each of the cover pages to this Amendment No. 3 are incorporated herein by reference.

 

Set forth below is the aggregate number of Ordinary Shares represented by American Depositary Shares (“ADS”) which may be deemed to be indirectly beneficially owned by the Reporting Persons, that may be acquired upon conversion of Ordinary Shares represented by ADS that may be acquired upon conversion of 6% convertible notes with a conversion price of 17.4 pence per Ordinary Share due August 3, 2023 (“Tranche 1 Notes”), subject to the limitations on conversion described below. Each ADS represents 5 Ordinary Shares of the Issuer.

 

 

The information set forth below is based on 643,204,794 Ordinary Shares outstanding as of June 9, 2023, as obtained in an email received from the Issuer on July 25, 2023, plus 14,604,391 Ordinary Shares represented by 2,920,878 ADS that may be acquired upon conversion of Tranche 1 Notes, subject to the limitations on conversion described below and 9,645,200 Ordinary Shares represented by 1,929,040 ADS issued in a conversion of Tranche 1 Notes by the Funds on July 21, 2023. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.

 

Name  Number of Ordinary Shares
we own or have the right to
acquire within 60 days
   Percent of
Class
Outs tanding
 
667, L.P.   1,060,040    0.2%
Baker Brothers Life Sciences, L.P.   13,544,351    2.0%
Total   14,604,391    2.2%

 

The Tranche 1 Notes are only convertible to the extent that upon giving effect or immediately prior to such conversion the holders thereof, their affiliates and any persons who are members of a Section 13(d) group with the holders or its affiliates would beneficially own in the aggregate, for purposes of Section 13(d) of the Exchange Act, no more than 9.99% of the outstanding Ordinary Shares after conversion (“Notes Beneficial Ownership Limitation”, and together with the Warrants Beneficial Ownership Limitation, the “Beneficial Ownership Limitations”). By written notice to the Issuer, the Funds may from time to time increase or decrease the Notes Beneficial Ownership Limitation applicable to that Fund to any other percentage not in excess of 19.99%. Any such increase will not be effective until the 61st day after such notice is delivered to the Issuer. As a result of this restriction, the number of Ordinary Shares that may be issued upon exercise of the Tranche 1 Notes by the above holders may change depending upon changes in the outstanding Ordinary Shares.

 

 

Pursuant to the management agreements, as amended, among the Adviser, the Funds and their respective general partners, the Funds’ respective general partners relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds and thus the Adviser has complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments.

 

The Adviser GP, Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds.

 

Item 5        Ownership of Five Percent or Less of a Class:

 

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following x.

 

Item 6      Ownership of More than Five Percent on Behalf of Another Person:

 

N/A

 

Item 7 Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person:

 

The information in Item 4 is incorporated herein by reference.

 

Item 8 Identification and Classification of Members of the Group:

 

N/A

 

Item 9 Notice of Dissolution of Group:

 

N/A

 

Item 10 Certification:

 

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

 

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

August 10, 2023

 

 

BAKER BROS. ADVISORS LP

 

By: Baker Bros. Advisors (GP) LLC, its general partner

     
  By: /s/ Scott L. Lessing
   

Name: Scott L. Lessing

Title: President

 

  BAKER BROS. ADVISORS (GP) LLC
     
  By: /s/ Scott L. Lessing
   

Name: Scott L. Lessing

Title: President

 

    /s/ Julian C. Baker
    Julian C. Baker
     
    /s/ Felix J. Baker
    Felix J. Baker