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"Insiders might sell their shares for any number of reasons, but they buy them for only one:
they think the price will rise" - Peter Lynch ==>> What is insider trading>> |

| Transaction & Date | Reported Date |
Company | Symbol | Insider Relationship |
Shares Traded | Average Price | Total Amount |
Shares Ownership |
Filing |
| 2009-08-10 Purchase |
2009-08-10 5:03 pm | INSPIRE PHARMACEUTICALS INC | ISPH | LEFF JONATHAN S (Director) | 8,888,888 | $4.5 | $39,999,996 | 22,907,488 (Indirect) | View |
| 2008-05-29 Purchase |
2008-05-30 4:08 pm | ALLOS THERAPEUTICS INC | ALTH | LEFF JONATHAN S (Director) | 3,500,000 | $5.64 | $19,740,000 | 26,124,430 (Indirect) |
View |
| 2008-03-07 Purchase |
2008-03-11 4:34 pm |
ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 56,722 | $8.617 | $488,791 | 9,077,471 (Indirect) |
View |
| 2008-03-05 Purchase |
2008-03-07 4:22 pm | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 98,254 | $9.335 | $917,178 | 8,840,267 (Indirect) |
View |
| 2008-03-03 Purchase | 2008-03-05 4:15 pm |
ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 139,536 | $9.617 | $1,341,887 | 8,541,549 (Indirect) | View |
| 2008-02-28- -2008-02-29 Purchase | 2008-03-03 4:15 pm | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 103,151 | $10 | $1,031,847 | 8,402,013 (Indirect) |
View |
| 2008-02-25- -2008-02-26 Purchase |
2008-02-27 4:13 pm | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 146,900 | $9.605 | $1,410,944 | 8,271,420 (Indirect) | View |
| 2008-02-21 Purchase | 2008-02-25 4:10 pm |
ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 96,570 | $9.145 | $883,096 | 7,897,090 (Indirect) | View |
| 2007-09-13 Purchase | 2007-09-17 4:05 pm | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 73,972 | $11.71 | $866,351 | 7,621,384 (Indirect) | View |
| 2007-09-11- -2007-09-12 Purchase | 2007-09-13 4:03 pm | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 223,783 | $11.62 | $2,600,780 | 7,447,543 (Indirect) |
View |
| 2007-05-30 Purchase | 2007-05-31 12:10 pm | SUNESIS PHARMACEUTICALS INC | SNSS | LEFF JONATHAN S (Director) | 677,200 | $4.43 | $2,999,996 | 4,304,075 (Indirect) |
View |
| Transaction & Date | Reported Date |
Company | Symbol | Insider Relationship |
Shares Traded |
Average Price |
Total Amount |
Shares Ownership |
Filing |
| 2008-07-25 Purchase |
2008-07-28 4:31 pm |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 4,999,982 | $0 | $0 | 13,571,411 (Indirect) |
View |
| 2007-10-31 Purchase |
2007-11-01 4:02 pm |
INSPIRE PHARMACEUTICALS INC | ISPH | LEFF JONATHAN S (Director) | 14,018,600 | $0 | $0 | 14,018,600 (Indirect) |
View |
| Transaction & Date | Reported Date |
Exercisable Expiration | Company | Symbol | Insider Relationship |
Shares Traded |
Conversion Price | Shares Ownership | Filing |
| 2009-05-21 Option Award |
2009-06-24 8:05 pm | 2009-06-21 2019-05-21 |
INTERMUNE INC | ITMN | LEFF JONATHAN S (Director) | 12,000 | $11.33 | 224,449 (Direct) | View |
| 2009-06-23 Option Award | 2009-06-23 6:41 pm |
2010-06-23 2019-06-23 |
ALLOS THERAPEUTICS INC | ALTH | LEFF JONATHAN S (Director) | 20,000 | $7.33 | 20,000 (Direct) | View |
| 2009-06-10 Option Award |
2009-06-11 4:46 pm | N/A 2019-06-10 |
ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 12,000 | $4.61 | 12,000 (Direct) |
View |
| 2009-06-05 Option Award |
2009-06-09 4:13 pm |
N/A 2016-06-05 |
INSPIRE PHARMACEUTICALS INC | ISPH | LEFF JONATHAN S (Director) | 30,000 | $5.05 | 30,000 (Direct) | View |
| 2008-07-25 Purchase | 2008-07-28 4:31 pm | N/A N/A |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 192,307 | $0 | 0 (Indirect) | View |
| 2008-06-24 Option Award | 2008-06-26 5:46 pm | 2009-06-24 2018-06-24 | ALLOS THERAPEUTICS INC | ALTH | LEFF JONATHAN S (Director) | 20,000 | $6.3 | 20,000 (Direct) | View |
| 2008-06-18 Option Award | 2008-06-19 1:09 pm |
N/A 2018-06-18 | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 12,000 | $7.9 | 12,000 (Direct) | View |
| 2008-06-15 Option Award |
2008-06-17 2:37 pm | N/A 2018-06-15 | NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $0.91 | 2,500 (Direct) |
View |
| 2008-06-12 Option Award |
2008-06-13 08:34 am | N/A 2018-06-12 | Altus Pharmaceuticals Inc. | ALTU | LEFF JONATHAN S (Director 10% owner) | 8,722 | $3.93 | 8,722 (Direct) |
View |
| 2008-06-10 Option Award | 2008-06-12 4:00 pm | N/A 2015-06-09 | INSPIRE PHARMACEUTICALS INC | ISPH | LEFF JONATHAN S (Director) | 30,000 | $5 | 30,000 (Direct) |
View |
| 2008-06-05 Option Award | 2008-06-05 4:52 pm |
2008-07-05 2018-06-05 | SUNESIS PHARMACEUTICALS INC | SNSS | LEFF JONATHAN S (Director 10% owner) | 10,000 | $1.77 | 10,000 (Direct) |
View |
| 2008-05-13 Option Award | 2008-05-15 3:16 pm | 2008-06-13 2018-05-13 | INTERMUNE INC | ITMN | LEFF JONATHAN S (Director) | 12,000 | $15.34 | 212,499 (Direct) | View |
| 2008-04-11 Purchase | 2008-04-14 4:51 pm |
N/A N/A |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 192,307 | $0 | 192,307 (Indirect) |
View |
| 2008-04-11 Purchase | 2008-04-14 4:51 pm |
N/A 2013-04-11 | NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 192,307 | $2.3 | 192,307 (Indirect) |
View |
| 2008-03-15 Option Award |
2008-03-18 2:11 pm |
N/A 2018-03-15 |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $1.59 | 2,500 (Direct) | View |
| 2007-12-15 Option Award | 2007-12-17 3:36 pm | N/A 2017-12-15 | NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $2.96 | 2,500 (Direct) |
View |
| 2007-10-31 Purchase |
2007-11-01 4:02 pm | N/A N/A |
INSPIRE PHARMACEUTICALS INC | ISPH | LEFF JONATHAN S (Director) | 140,186 | $0 | 0 (Indirect) |
View |
| 2007-09-15 Option Award | 2007-09-17 10:58 am | N/A 2017-09-15 |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $4.9 | 2,500 (Direct) |
View |
| 2007-06-05 Option Award |
2007-07-02 6:53 pm |
2007-07-05 2017-06-05 |
SUNESIS PHARMACEUTICALS INC | SNSS | LEFF JONATHAN S (Director 10% owner) | 10,000 | $4.23 | 10,000 (Direct) |
View |
| 2007-06-27 Option Award | 2007-06-28 11:15 am |
N/A 2017-06-27 | Altus Pharmaceuticals Inc. | ALTU | LEFF JONATHAN S (Director 10% owner) | 8,722 | $11.85 | 8,722 (Direct) | View |
| 2007-06-21 Option Award | 2007-06-25 4:40 pm |
N/A 2017-06-21 | ZYMOGENETICS INC | ZGEN | LEFF JONATHAN S (Director) | 12,000 | $15.11 | 12,000 (Direct) | View |
| 2007-06-19 Option Award |
2007-06-21 5:40 pm | 2008-06-19 2017-06-19 |
ALLOS THERAPEUTICS INC | ALTH | LEFF JONATHAN S (Director) | 20,000 | $5.63 | 20,000 (Direct) | View |
| 2007-06-15 Option Award | 2007-06-18 2:39 pm | N/A 2017-06-15 |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $8.46 | 2,500 (Direct) |
View |
| 2007-06-15 Option Award | 2007-06-15 5:13 pm |
N/A 2017-06-15 |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $8.47 | 2,500 (Direct) | View |
| 2007-06-07 Option Award |
2007-06-08 4:30 pm | N/A 2017-06-07 |
NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 1,500 | $7.85 | 1,500 (Direct) |
View |
| 2007-05-15 Option Award | 2007-05-17 9:10 pm | 2007-06-15 2017-05-15 |
INTERMUNE INC | ITMN | LEFF JONATHAN S (Director) | 12,000 | $25.55 | 200,499 (Direct) | View |
| 2007-03-15 Option Award | 2007-03-15 6:01 pm | N/A 2017-03-15 | NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $6.53 | 2,500 (Direct) | View |
| 2007-02-02 Option Award | 2007-02-05 4:53 pm |
2007-02-02 2017-02-02 | Altus Pharmaceuticals Inc. | ALTU | LEFF JONATHAN S (Director 10% owner) | 68 | $18.45 | 68 (Direct) | View |
| 2006-12-15 Option Award |
2006-12-18 3:11 pm | N/A 2016-12-15 | NEUROGEN CORP | NRGN | LEFF JONATHAN S (Director) | 2,500 | $5.78 | 2,500 (Direct) |
View |
| 2006-11-15 Option Award | 2006-11-17 12:08 pm |
N/A 2016-11-15 |
Altus Pharmaceuticals Inc. | ALTU | LEFF JONATHAN S (Director 10% owner) | 8,722 | $18.98 | 8,722 (Direct) | View |
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