Sec Form 4 Filing - Lamb Peter @ EXELIXIS, INC. - 2015-10-12

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Lamb Peter 2. Issuer Name and Ticker or Trading Symbol EXELIXIS, INC. [ EXEL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) EVP, Discovery Research & CSO (Last) (First) (Middle) C/O EXELIXIS, INC., 210 E. GRAND AVE. 3. Date of Earliest Transaction (MM/DD/YY) 10/12/2015 (Street) SOUTH SAN FRANCISCO, CA94080 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 10/12/2015 M 525 A $ 5.63 36,998 D Common Stock 10/12/2015 M 1,400 A $ 5.63 38,398 D Common Stock 10/12/2015 M 2,500 A $ 5.63 40,898 D Common Stock 10/12/2015 M 8,000 A $ 5.63 48,898 D Common Stock 10/12/2015 M 20,000 A $ 5.63 68,898 D Common Stock 10/12/2015 M 28,000 A $ 5.63 96,898 D Common Stock 10/12/2015 M 84,000 A $ 5.63 180,898 D Common Stock 10/12/2015 M 19,333 A $ 5.63 200,231 D Common Stock 10/12/2015 M 39,999 A $ 5.63 240,230 D Common Stock 10/12/2015 M 39,583 A $ 5.63 279,813 D Common Stock 10/12/2015 M 56,936 A $ 5.63 336,749 D Common Stock 10/12/2015 S 300,276 D $ 5.839 ( 1 ) 36,473 D Common Stock 10/13/2015 M 600 A $ 5.63 37,073 D Common Stock 10/13/2015 S 600 D $ 5.8 36,473 D Common Stock 14,478 I By 401(k) ( 2 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Option (right to buy) $ 5.63 10/12/2015 M 525 08/05/2010( 3 ) 10/17/2015 Common Stock 525 $ 0 242,815 D Option (right to buy) $ 5.63 10/12/2015 M 1,400 08/05/2010( 3 ) 10/17/2015 Common Stock 1,400 $ 0 241,415 D Option (right to buy) $ 5.63 10/12/2015 M 2,500 08/05/2010( 3 ) 10/17/2015 Common Stock 2,500 $ 0 238,915 D Option (right to buy) $ 5.63 10/12/2015 M 8,000 08/05/2010( 3 ) 10/17/2015 Common Stock 8,000 $ 0 230,915 D Option (right to buy) $ 5.63 10/12/2015 M 20,000 08/05/2010( 3 ) 10/17/2015 Common Stock 20,000 $ 0 210,915 D Option (right to buy) $ 5.63 10/12/2015 M 28,000 08/05/2010( 3 ) 10/17/2015 Common Stock 28,000 $ 0 182,915 D Option (right to buy) $ 5.63 10/12/2015 M 84,000 08/05/2010( 3 ) 10/17/2015 Common Stock 84,000 $ 0 98,915 D Option (right to buy) $ 5.63 10/12/2015 M 19,333 08/05/2010( 3 ) 10/17/2015 Common Stock 19,333 $ 0 79,582 D Option (right to buy) $ 5.63 10/12/2015 M 39,999 08/05/2010( 3 ) 10/17/2015 Common Stock 39,999 $ 0 39,583 D Option (right to buy) $ 5.63 10/12/2015 M 39,583 08/05/2010( 3 ) 10/17/2015 Common Stock 39,583 $ 0 0 D Option (right to buy) $ 5.63 10/12/2015 M 56,936 08/05/2010( 4 ) 10/17/2015 Common Stock 56,936 $ 0 52,149 D Option (right to buy) $ 5.63 10/13/2015 M 600 08/05/2010( 4 ) 10/17/2015 Common Stock 600 $ 0 51,549 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Lamb Peter C/O EXELIXIS, INC. 210 E. GRAND AVE. SOUTH SAN FRANCISCO, CA94080 EVP, Discovery Research & CSO Signatures /s/ Jeffrey J. Hessekiel, Attorney in Fact 10/13/2015 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.80 to $6.00, inclusive. The reporting person undertakes to provide to Exelixis, Inc., any security holder of Exelixis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above. ( 2 )Represents 14,478 shares of Exelixis, Inc. common stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of October 13, 2015. ( 3 )Option granted pursuant to Issuer's 2000 Equity Incentive Plan. One hundred percent (100%) of the shares vest one year from date of grant. ( 4 )Option granted pursuant to Issuer's 2000 Equity Incentive Plan. Thirty-three percent (33%) of the shares vest one year from date of grant, and the remaining shares vest in 24 equal monthly installments thereafter.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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