Sec Form 4 Filing - Schuler Henri George @ VERMILLION, INC. - 2018-06-21

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Schuler Henri George 2. Issuer Name and Ticker or Trading Symbol VERMILLION, INC. [ VRML] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 100 N. FIELD DRIVE, SUITE 360 3. Date of Earliest Transaction (MM/DD/YY) 06/21/2018 (Street) LAKE FOREST, IL60045 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, par value $0.001 06/21/2018 C 245,900 A $ 1 ( 7 ) 3,797,057 I By Tanya Eva Schuler Trust ( 1 ) ( 6 ) Common Stock, par value $0.001 06/21/2018 C 245,800 A $ 1 ( 7 ) 3,796,957 I By Therese Heidi Schuler Trust ( 2 ) ( 6 ) Common Stock, par value $0.001 06/21/2018 C 54,700 A $ 1 ( 7 ) 1,040,068 I By Schuler GC 2010 Continuation Trust ( 3 ) ( 6 ) Common Stock, par value $0.001 06/21/2018 C 245,800 A $ 1 ( 7 ) 1,253,177 I By Schuler Grandchildren LLC ( 4 ) ( 6 ) Common Stock, par value $0.001 141,304 I By Seascape Partners L.P. ( 5 ) ( 6 ) Common Stock, par value $0.001 26,000 I By spouse ( 6 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series B Convertible Preferred Stock (Right to Buy) $ 1 ( 7 ) 06/21/2018 C 2,459 06/21/2018 ( 8 ) Common Stock 245,900 $ 0 0 I By Tanya Eva Schuler Trust ( 1 ) ( 6 ) Series B Convertible Preferred Stock (Right to Buy) $ 1 ( 7 ) 06/21/2018 C 2,458 06/21/2018 ( 8 ) Common Stock 245,800 $ 0 2,458 I By Therese Heidi Schuler Trust ( 2 ) ( 6 ) Series B Convertible Preferred Stock (Right to Buy) $ 1 ( 7 ) 06/21/2018 C 547 06/21/2018 ( 8 ) Common Stock 54,700 $ 0 0 I By Schuler GC 2010 Continuation Trust ( 3 ) ( 6 ) Series B Convertible Preferred Stock (Right to Buy) $ 1 ( 7 ) 06/21/2018 C 2,458 06/21/2018 ( 8 ) Common Stock 245,800 $ 0 0 I By Schuler Grandchildren LLC ( 4 ) ( 6 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Schuler Henri George 100 N. FIELD DRIVE SUITE 360 LAKE FOREST, IL60045 X Signatures /s/ H. George Schuler 06/25/2018 Signature of Reporting Person Date

Explanation of Responses:

( 1 )These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust. ( 2 )These Shares and Preferred Stock are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust. ( 3 )These Shares and Preferred Stock are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust. ( 4 )These Shares and Preferred Stock are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC. ( 5 )These Shares are directly owned by Seascape Partners L.P., a family limited partnership. H. George Schuler is the manager of Seascape Partners L.P. ( 6 )The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. ( 7 )On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share.. ( 8 )The Preferred Stock has no expiration date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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