Sec Form 4 Filing - SACHDEV RAKESH @ SIGMA ALDRICH CORP - 2015-11-18

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person SACHDEV RAKESH 2. Issuer Name and Ticker or Trading Symbol SIGMA ALDRICH CORP [ SIAL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) President & CEO (Last) (First) (Middle) C/O SIGMA-ALDRICH CORPORATION, 3050 SPRUCE STREET 3. Date of Earliest Transaction (MM/DD/YY) 11/18/2015 (Street) ST LOUIS, MO63103 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock ( 1 ) 11/18/2015 A 11,000 A $ 0 ( 2 ) 51,533 D Common Stock ( 1 ) 11/18/2015 D 11,000 D $ 140 ( 2 ) 40,533 D Common Stock ( 1 ) 11/18/2015 A 15,145 A $ 0 ( 2 ) 55,678 D Common Stock ( 1 ) 11/18/2015 D 15,145 D $ 140 ( 2 ) 40,533 D Common Stock ( 1 ) 11/18/2015 A 15,145 A $ 0 ( 2 ) 55,678 D Common Stock ( 1 ) 11/18/2015 D 15,145 D $ 140 ( 2 ) 40,533 D Common Stock ( 1 ) 11/18/2015 A 10,000 A $ 0 ( 2 ) 50,533 D Common Stock ( 1 ) 11/18/2015 D 10,000 D $ 140 ( 2 ) 40,533 D Common Stock ( 1 ) 11/18/2015 D 40,533 D $ 140 0 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares NQ Stock Option, Right to Buy $ 62.49 11/18/2015 D 65,240 02/14/2012 02/14/2021 Common Stock 65,240 $ 62.49 ( 3 ) 0 D NQ Stock Option Right to Buy $ 70.32 11/18/2015 D 76,578 02/14/2013 02/14/2022 Common Stock 76,578 $ 70.32 ( 3 ) 0 D ISO Stock Option Right To Buy $ 76.34 11/18/2015 D 1,309 02/11/2014 02/11/2023 Common Stock 1,309 $ 76.34 ( 3 ) 0 D NQ Stock Option Right to Buy $ 76.34 11/18/2015 D 87,881 02/11/2014 02/11/2023 Common Stock 87,881 $ 76.34 ( 3 ) 0 D NQ Stock Option Right to Buy $ 82.54 11/18/2015 D 130,000 09/03/2014 09/03/2023 Common Stock 130,000 $ 82.54 ( 3 ) 0 D ISO Stock Option Right To Buy $ 93.07 11/18/2015 D 1,074 02/10/2015 02/10/2024 Common Stock 1,074 $ 93.07 ( 3 ) 0 D NQ Stock Option Right to Buy $ 93.07 11/18/2015 D 63,836 02/10/2015 02/10/2024 Common Stock 63,836 $ 93.07 ( 3 ) 0 D Restricted Stock Unit $ 0 ( 1 ) 11/18/2015 D 11,000 02/11/2016 02/11/2016 Common Stock 11,000 $ 0 ( 4 ) 0 D Restricted Stock Unit $ 0 ( 1 ) 11/18/2015 D 10,000 02/10/2017 02/10/2017 Common Stock 10,000 $ 0 ( 4 ) 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other SACHDEV RAKESH C/O SIGMA-ALDRICH CORPORATION 3050 SPRUCE STREET ST LOUIS, MO63103 X President & CEO Signatures /s/ Jesica Betts, by Power of Attorney 11/19/2015 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Please see attached Exhibit A. Capitalized terms used herein and not otherwise defined shall have the meanings assigned to them in the attached Exhibit A. ( 2 )These performance-based restricted stock units, which provided for vesting three years of the date of the grant, subject to certain performance criteria were cancelled at the Effective Time (whether vested or unvested) in exchange for a cash payment equal to the Per-Share Merger Consideration. ( 3 )These stock options, which provided for vesting in three equal annual installments beginning on the first anniversary of the date of the grant, were cancelled at the Effective Time (whether vested or unvested) in exchange for a cash payment equal to the Per-Share Merger Consideration, less the exercise price of the option. ( 4 )These service-based restricted stock units, which provided for vesting 100% after three years of the date of the grant, were cancelled at the Effective Time in exchange for a cash payment equal to the Per-Share Merger Consideration.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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