Sec Form 4 Filing - SPARKLE BYTE LTD @ CASI Pharmaceuticals, Inc. - 2016-06-24

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person SPARKLE BYTE LTD 2. Issuer Name and Ticker or Trading Symbol CASI Pharmaceuticals, Inc. [ CASI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) P.O. BOX 957, OFFSHORE INCORPORATIONS CENTRE 3. Date of Earliest Transaction (MM/DD/YY) 06/24/2016 (Street) ROAD TOWN, TORTOLA, D800000 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 06/24/2016 P 3,753,855 A $ 1.19 ( 2 ) 8,498,765 D ( 1 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Warrant $ 1.69 06/24/2016 P 750,771 09/23/2016 09/23/2019 Common Stock 750,771 $ 0.025 ( 2 ) 1,699,753 D ( 1 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other SPARKLE BYTE LTD P.O. BOX 957 OFFSHORE INCORPORATIONS CENTRE ROAD TOWN, TORTOLA, D800000 X SNOW MOON LTD P.O. BOX 957 OFFSHORE INCORPORATIONS CENTRE ROAD TOWN, TORTOLA, D800000 X TIANJIN JINGRAN MANAGEMENT CENTER (LIMITED PARTNERSHIP) RM 1704-4920 KUANG SHI GUO JI TOWER A XIANGLUOWAN BUSINESS CTR FREE TRADE ZONE TIANJIN, F400000 X HE XIE AI QI INVESTMENT MANAGEMENT (BEIJING) CO., LTD. ROOM 5835, 5/F, SHENCHANG BUILDING 51 ZHICHUN ROAD, HAIDIAN DISTRICT BEIJING, F4100005 X Li Jianguang 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE BEIJING, F4100005 X Lin Dongliang 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE BEIJING, F4100005 X Yang Fei 34/F SOUTH TOWER, POLY INTERNATIONAL PLZ 1 EAST PAZHOUDADAO GUANGZHOU, F4510308 X Zhang Suyang RM 1105, AETNA TOWER, 107 ZUNYI RD SHANGHAI, F4200051 X Shong Hugo 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE BEIJING, F4100005 X Signatures /s/ Dongliang Lin, Director, on behalf of Sparkle Byte Limited 06/29/2016 Signature of Reporting Person Date /s/ Dongliang Lin, Director, on behalf of Snow Moon Limited 06/29/2016 Signature of Reporting Person Date /s/ Qiuyue Zhong, Representative, on behalf of Tianjin Jingran Management Center (Limited Partnership) 06/29/2016 Signature of Reporting Person Date /s/ Hugo Shong, Director, on behalf of He Xie Ai Qi Investment Management (Beijing) Co., Ltd. 06/29/2016 Signature of Reporting Person Date /s/ Jianguang Li 06/29/2016 Signature of Reporting Person Date /s/ Dongliang Lin 06/29/2016 Signature of Reporting Person Date /s/ Fei Yang 06/29/2016 Signature of Reporting Person Date /s/ Suyang Zhang 06/29/2016 Signature of Reporting Person Date /s/ Hugo Shong 06/29/2016 Signature of Reporting Person Date

Explanation of Responses:

( 1 )These securities are directly owned by Sparkle Byte Limited ("Sparkle Byte") and may be deemed to be indirectly beneficially owned by the other reporting persons. Snow Moon Limited ("Snow Moon") holds 100% of the equity interest of Sparkle Byte. Tianjin Jingran Management Center (Limited Partnership) ("Tianjin Jingran") holds 100% of the equity interest of Snow Moon. He Xie Ai Qi Investment Management (Beijing) Co., Ltd. ("He Xie Ai Qi") is the general partner of Tianjin Jingran. Jianguang Li, Dongliang Lin, Fei Yang and Suyang Zhang each holds 25% of the equity interest of He Xie Ai Qi. Jianguang Li, Dongliang Lin and Hugo Shong are the directors of He Xie Ai Qi. The filing of this statement by the reporting persons shall not be deemed an admission that such persons are, for purposes of Section 16 of the Securities and Exchange Act of 1934 or otherwise, the beneficial owner of any equity securities covered by this statement. ( 2 )The shares of common stock and the warrants were issued in units consisting of one share of common stock and a warrant to purchase 0.2 shares of common stock. The purchase price for one share was $1.190 and the purchase price for a warrant to purchase 0.2 shares of common stock is $0.025.The filing of this statement by the reporting persons shall not be deemed an admission that such persons are, for purposes of Section 16 of the Securities and Exchange Act of 1934 or otherwise, the beneficial owner of any equity securities covered by this statement.

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