Sec Form 4/A Filing - Pickett Denise @ AMERICAN EXPRESS CO - 2022-01-29

FORM 4/A Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Pickett Denise 2. Issuer Name and Ticker or Trading Symbol AMERICAN EXPRESS CO [ AXP] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Pres., GSG and TLS (Last) (First) (Middle) 200 VESEY STREET, AMERICAN EXPRESS TOWER 3. Date of Earliest Transaction (MM/DD/YY) 01/29/2022 (Street) NEW YORK, NY10285-5001 4. If Amendment, Date Original Filed (MM/DD/YY) 02/01/2022 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 01/29/2022 A( 1 ) 15,451 A $ 0 31,095.83 D Common Stock 01/29/2022 F( 2 ) 8,351 D $ 177.06 22,806.093( 3 ) D Common Stock 02/03/2022 S 7,000 D $ 183.955 15,806.093 D Common Stock 1,400.4375( 4 ) I by ESOP

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Employee Stock Option (Right to Buy) $ 100.96 01/29/2022 A( 5 ) 16,688 01/29/2022 01/29/2029 Common Stock 16,688 $ 0 16,688 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Pickett Denise 200 VESEY STREET, AMERICAN EXPRESS TOWER NEW YORK, NY10285-5001 Pres., GSG and TLS Signatures /s/ Kristina V. Fink, attorney-in-fact 02/07/2022 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents shares acquired pursuant to vesting of Restricted Stock Units that were granted to the reporting person in January 2019 and have vested based on the Company's 2019-21 average return on equity performance. ( 2 )The reported disposition represents the surrender of shares to satisfy tax obligations arising from the vesting of Restricted Stock Units. ( 3 )Includes shares acquired pursuant to dividend reinvestment. ( 4 )Includes shares held in the reporting person's account under the Company's Employee Stock Ownership Plan. ( 5 )The reported acquisition represents the vesting of Stock Options that were granted to the reported person on 1/29/2019. These options became exercisable on 1/29/2022 based on the Company's positive cumulative net income over the three year performance period.

Remarks: The original Form 4, filed on February 1, 2022, is being amended by this Form 4 amendment to include shares acquired pursuant to dividend reinvestment and shares held in the reporting person's account under the Company's Employee Stock Ownership Plan (as reflected in the footnotes above) that were inadvertently omitted in the original filing.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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