Sec Form 4 Filing - Mahmood Tahir Ph.D. @ Applied Molecular Transport Inc. - 2022-02-15

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Mahmood Tahir Ph.D. 2. Issuer Name and Ticker or Trading Symbol Applied Molecular Transport Inc. [ AMTI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O APPLIED MOLECULAR TRANSPORT INC., 450 EAST JAMIE COURT 3. Date of Earliest Transaction (MM/DD/YY) 02/15/2022 (Street) SOUTH SAN FRANCISCO, CA94080 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/15/2022 A 75,000( 1 ) A $ 0 78,000 D Common Stock 176,657 I By Irrevocable Trust( 2 ) Common Stock 334,632 I By GRAT( 3 ) Common Stock 3,088,711 I By Living Trust( 4 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 8.29 02/15/2022 A 350,000 03/15/2022( 5 ) 02/15/2032 Common Stock 350,000 $ 0 350,000 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Mahmood Tahir Ph.D. C/O APPLIED MOLECULAR TRANSPORT INC. 450 EAST JAMIE COURT SOUTH SAN FRANCISCO, CA94080 X Chief Executive Officer Signatures /s/ Brandon Hants Attorney-in-Fact for Tahir Mahmood 02/16/2022 Signature of Reporting Person Date

Explanation of Responses:

( 1 )These securities are Restricted Stock Units (RSUs). Each RSU represents a contingent right to receive one shares of the Issuer's Common Stock. 5/48ths of the RSUs shall vest on June 1, 2022 and 1/16th of the RSUs shall vest quarterly thereafter, subject to the Reporting Person continuing as a service provider through each such date. ( 2 )These shares are held directly by The Mahmood 2017 Irrevocable Trust for which the Reporting Person serves as trustee and over which shares the Reporting Person hold voting and dispositive power. ( 3 )These shares are held directly by the Tahir Mahmood 2019 Annuity Trust for which the Reporting Person serves as trustee and over which shares the Reporting Person holds voting and dispositive power. ( 4 )These shares are held directly by the Mrsny-Daugherty Living Trust for which the Reporting Person and his spouse are co-trustees, and over which the Reporting Person and his spouse hold voting and dispositive power. ( 5 )1/48th of the shares subject to the option shall become vested and exercisable on the Exercisable Date set forth above and 1/48th of the shares subject to the option shall continue to vest each month thereafter, provided that Reporting Person is a service provider to the Issuer as of each such vesting date.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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