Sec Form 4 Filing - Madsen Julia @ STERIS plc - 2021-06-01

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Madsen Julia 2. Issuer Name and Ticker or Trading Symbol STERIS plc [ STE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Senior VP, Life Sciences (Last) (First) (Middle) C/O 70 SIR ROGER'S QUAY 3. Date of Earliest Transaction (MM/DD/YY) 06/01/2021 (Street) DUBLIN, L22 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 06/01/2021 D 107 ( 1 ) D $ 188.43 4,534 ( 2 ) D Ordinary Shares 06/01/2021 D 42 ( 3 ) D $ 188.43 4,492 ( 2 ) D Ordinary Shares 06/01/2021 D 32 ( 4 ) D $ 188.43 4,460 ( 2 ) D Ordinary Shares 06/01/2021 D 43 ( 5 ) D $ 188.43 4,417 ( 2 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Trans action(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Madsen Julia C/O 70 SIR ROGER'S QUAY DUBLIN, L22 Senior VP, Life Sciences Signatures /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 06/02/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )107 shares were withheld from the 308 restricted shares that vested on June 1, 2021. These 107 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 308 ordinary shares are part of an award of 1,232 ordinary shares that were awarded to Ms. Madsen on May 30, 2017. These vested shares were valued at the NYSE closing market price on June 1, 2021. ( 2 )2,070 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 349 on October 1, 2021; 121 on May 31, 2022; 92 on May 31, 2022; 123 on June 1, 2022; 349 on October 3, 2022; 92 on May 31, 2023; 349 on October 2, 2023; 123 on June 1, 2023; 123 on June 3, 2024 and 349 on October 1, 2024. ( 3 )42 shares were withheld from the 121 restricted shares that vested on June 1, 2021. These 42 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 121 ordinary shares are part of an award of 484 ordinary shares that were awarded to Ms. Madsen on May 31, 2018. These vested shares were valued at the NYSE closing market price on June 1, 2021. ( 4 )32 shares were withheld from the 92 restricted shares that vested on June 1, 2021. These 32 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 92 ordinary shares are part of an award of 368 ordinary shares that were awarded to Ms. Madsen on May 31, 2019. These vested shares were valued at the NYSE closing market price on June 1, 2021. ( 5 )43 shares were withheld from the 123 restricted shares that vested on June 1, 2021. These 43 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 123 ordinary shares are part of an award of 492 ordinary shares that were awarded to Ms. Madsen on June 1, 2020. These vested shares were valued at the NYSE closing market price on June 1, 2021.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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