Sec Form 4 Filing - Jovan-Embiricos Morana @ TCR2 THERAPEUTICS INC. - 2019-12-18

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Jovan-Embiricos Morana 2. Issuer Name and Ticker or Trading Symbol TCR2 THERAPEUTICS INC. [ TCRR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O LJ FIDUCIARY, 8, RUE SAINT-LEGER, 3. Date of Earliest Transaction (MM/DD/YY) 12/18/2019 (Street) GENEVA, V8CH-1205 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 12/18/2019 S 458 D $ 17.006 89,217 I By Fund ( 1 ) Common Stock 12/18/2019 S 2,433 D $ 17.006 191,309 I By Fund ( 2 ) Common Stock 12/19/2019 S 6,642 D $ 16.4714 82,575 I By Fund ( 1 ) Common Stock 12/19/2019 S 35,323 D $ 16.4714 155,986 I By Fund ( 2 ) Common Stock 12/20/2019 J( 3 ) 586,153 D $ 0 713,723 I By Fund ( 4 ) Common Stock 12/20/2019 J( 5 ) 13,847 D $ 0 161,024 I By Fund ( 6 ) Common Stock 361,665 I By Fund ( 7 ) Common Stock 432,319 I By Fund ( 8 ) Common Stock 330,238 I By Fund ( 9 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Jovan-Embiricos Morana C/O LJ FIDUCIARY, 8, RUE SAINT-LEGER GENEVA, V8CH-1205 X Globeways Holdings Ltd 3RD FLOOR, GENEVE PLACE, WATERFRONT DR PO BOX 3175, ROAD TOWN, TORTOLA, BVI GENEVA, V8CH-1205 X Globeways Holdings II Ltd 3RD FLOOR, GENEVE PLACE, WATERFRONT DR PO BOX 3175, ROAD TOWN, TORTOLA, BVI GENEVA, V8CH-1205 X F2 Capital I 2015 Ltd C/O LJ FIDUCIARY, 8, RUE SAINT-LEGER GENEVA, V8CH-1205 X F2 Captial I 2017 Ltd C/O LJ FIDUCIARY, 8, RUE SAINT-LEGER GENEVA, V8CH-1205 X F2 MG Ltd C/O LJ FIDUCIARY, 8, RUE SAINT-LEGER GENEVA, V8CH-1205 X F2 Bioscience II 2017 Ltd C/O LJ PARTNERSHIP, 8, RUE SAINT-LEGER, GENEVA, V8CH-1205 X F2 - TPO Investments LLC C/O SINGER MCKEON, 8 WEST 38TH STREET, SUITE 1001 NEW YORK, NY10018 X F2 BBG LLC C/O SINGER MCKEON INC, 8 WEST 38TH ST SUITE 1001 NEW YORK, NY10018 X F2 Capital I 2019, LLC C/O SINGER MCKEON INC, 8 WEST 38TH ST SUITE 1001 NEW YORK, NY10018 X Signatures /s/ Morana Jovan-Embiricos 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for Globeways Holdings Limited 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for Globeways Holdings II Limited 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 Capital I 2015 Limited 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 Capital I 2017 Limited 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 MG Limited 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2-TPO Investments, LLC 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 BBG LLC 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 Capital I 2019, LLC 12/20/2019 Signature of Reporting Person Date /s/ Morana Jovan-Embiricos for F2 Bioscience II 2017 Ltd. 12/20/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The reported securities are owned directly by F2 Capital I 2019, LLC. Globeways Holdings II Limited is the appointed manager of F2 Capital I 2019, LLC and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Capital I 2019, LLC. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings II Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings II Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 2 )The reported securities are owned directly by F2 Bioscience II 2017 Limited. Globeways Holdings Limited is the appointed manager of F2 Bioscience II 2017 Limited and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Bioscience II 2017 Limited. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 3 )Represents a pro-rata in-kind distribution of common stock by F2 Capital I 2015 Limited without consideration to its partners. ( 4 )The reported securities are owned directly by F2 Capital I 2015 Limited. Globeways Holdings Limited is the appointed manager of F2 Capital I 2015 Limited and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Capital I 2015 Limited. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 5 )Represents a pro-rata in-kind distribution of common stock by F2 BBG LLC without consideration to its partners. ( 6 )The reported securities are owned directly by F2 BBG LLC. Globeways Holdings II Limited is the appointed manager of F2 BBG LLC and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 BBG LLC. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings II Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings II Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 7 )The reported securities are owned directly by F2 MG Limited. Globeways Holdings Limited is the appointed manager of F2 MG Limited and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 MG Limited. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 8 )The reported securities are owned directly by F2-TPO Investments, LLC. Globeways Holdings II Limited is the appointed manager of F2-TPO Investments, LLC and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2-TPO Investments, LLC. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings II Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings II Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein. ( 9 )The reported securities are owned directly by F2 Capital I 2017 Limited. Globeways Holdings Limited is the appointed manager of F2 Capital I 2017 Limited and has sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Capital I 2017 Limited. Morana Jovan-Embiricos is the founding director and shareholder of Globeways Holdings Limited and has the sole power to vote upon the acquisition, holding and disposal of all shares and warrants held by Globeways Holdings Limited. Each of the reporting persons disclaims beneficial ownership of the securities reported herein except to the extent of their pecuniary interest therein.

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