Sec Form 4 Filing - HUNT RONALD @ Harpoon Therapeutics, Inc. - 2018-11-09

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person HUNT RONALD 2. Issuer Name and Ticker or Trading Symbol Harpoon Therapeutics, Inc. [ HARP] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O NEW LEAF VENTURES, 7 TIMES SQUARE, SUITE 3502 3. Date of Earliest Transaction (MM/DD/YY) 11/09/2018 (Street) NEW YORK, NY10036 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/12/2019 C 1,564,272 A 1,564,272 I See footnote ( 2 ) ( 3 ) Common Stock 02/12/2019 C 464,281 A 2,028,553 I See footnote ( 2 ) ( 3 ) Common Stock 02/12/2019 C 464,281 A 464,281 I See footnote ( 4 ) ( 5 ) Common Stock 02/12/2019 P 214,286 A $ 14 2,242,839 I See footnote ( 2 ) ( 3 ) Common Stock 02/12/2019 P 214,285 A $ 14 678,566 I See footnote ( 4 ) ( 5 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Series C Convertible Preferred Stock ( 1 ) 11/09/2018 P( 6 ) 464,281 ( 1 ) ( 1 ) Common Stock 464,281 ( 1 ) 464,281 I See footnote ( 2 ) ( 3 ) Series C Convertible Preferred Stock ( 1 ) 11/09/2018 P( 6 ) 464,281 ( 1 ) ( 1 ) Common Stock 464,281 ( 1 ) 464,281 I See footnote ( 4 ) ( 5 ) Director Stock Option (right to buy) $ 2.12 12/19/2018 A( 6 ) 20,335 ( 7 ) 12/19/2028 Common Stock 20,335 $ 0 20,335 D Series B Convertible Preferred Stock ( 1 ) 02/12/2019 C 1,564,272 ( 1 ) ( 1 ) Common Stock 1,564,272 ( 1 ) 0 I See footnote ( 2 ) ( 3 ) Series C Convertible Preferred Stock ( 1 ) 02/12/2019 C 464,281 ( 1 ) ( 1 ) Common Stock 464,281 ( 1 ) 0 I See footnote ( 2 ) ( 3 ) Series C Convertible Preferred Stock ( 1 ) 02/12/2019 C 464,281 ( 1 ) ( 1 ) Common Stock 464,281 ( 1 ) 0 I See footnote ( 4 ) ( 5 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other HUNT RONALD C/O NEW LEAF VENTURES 7 TIMES SQUARE, SUITE 3502 NEW YORK, NY10036 X X Signatures /s/ Ronald Hunt by Winston Macaraeg, Attorney-in-Fact 02/14/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )All series of convertible preferred stock automatically converted into shares of the Issuer's common stock on a 1-for-1 basis, for no additional consideration, upon the closing of the Issuer's initial public offering. ( 2 )These shares are held directly by New Leaf Ventures III, L.P. ("NLV-III"). The general partner of NLV-III is New Leaf Venture Associates III, L.P. ("NLVA-III"). The general partner of NLVA-III is New Leaf Venture Management III, L.L.C. ("Management-III"). Each of NLVA-III and Management-III disclaim beneficial ownership of these securities and this report shall not be deemed an admission that NLVA-III or Management-III are beneficial owners of such securities for purposes of Section 16 or any other purpose, except to the extent of their respective pecuniary interests therein. ( 3 )Each of Ronald M. Hunt, a member of the Issuer's board of directors, Vijay K. Lathi, and Liam T. Ratcliffe, the managers of Management-III (the "NLV-III Managers"), may each be deemed to have shared voting and investment power with respect to these securities. Each of the NLV-III Managers disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. ( 4 )These shares are held directly by New Leaf Ventures Biopharma Opportunities II, L.P. ("BPO-II"). The general partner of BPO-II is New Leaf BPO Associates II, L.P. ("NLBA-II"). The general partner of NLBA-II is New Leaf BPO Management II, L.L.C. ("BPO Management-II"). Each of NLBA-II and BPO Management-II disclaim beneficial ownership of these securities and this report shall not be deemed an admission that NLBA-II or BPO Management-II are beneficial owners of such securities for purposes of Section 16 or any other purpose, except to the extent of their respective pecun iary interests therein. ( 5 )Each of Ronald M. Hunt, Vijay K. Lathi, Liam T. Ratcliffe and Isaac A. Manke, the managers of BPO Management-II (the "BPO-II Managers"), may each be deemed to have shared voting and investment power with respect to these securities. Each of the BPO-II Managers disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. ( 6 )Reflects a transaction with the Issuer prior to its Section 12 registration which occurred within 6 months of the post-registration transaction reported on this Form 4. ( 7 )The stock option vests in three annual installments starting on December 19, 2019, until such time as the option is 100% vested, subject to the continuing service of the Reporting Person on each vesting date.

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