Sec Form 4 Filing - CARUSO RICHARD E @ SeaSpine Holdings Corp - 2019-05-06

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person CARUSO RICHARD E 2. Issuer Name and Ticker or Trading Symbol SeaSpine Holdings Corp [ SPNE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 795 E LANCASTER AVENUE, SUITE 200 3. Date of Earliest Transaction (MM/DD/YY) 05/06/2019 (Street) VILLANOVA, PA19085 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 05/06/2019 X 5,020 A $ 14.15 20,477 D Common Stock 05/06/2019 S 5,020 D $ 15.17 ( 1 ) 15,457 D Common Stock 1,997,068 ( 2 ) ( 3 ) I By Tru St Partnership LP Common Stock 24,382 ( 2 ) ( 3 ) I By the Uncommon Individual Foundation Common Stock 7,779 ( 2 ) ( 3 ) I By Provco Leasing Corporation

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (right to buy) $ 14.15 05/06/2019 X 5,020 07/01/2015 05/17/2019 Common Stock 5,020 $ 0 0 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other CARUSO RICHARD E 795 E LANCASTER AVENUE, SUITE 200 VILLANOVA, PA19085 X Signatures /s/ Paul Benny, Attorney-in-Fact for Richard E Caruso 05/08/2019 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The price reported is a weighted average. These shares were sold in multiple transactions at prices ranging from not less than $15.09 to not more than $15.26. The reporting person undertakes to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. ( 2 )The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. ( 3 )Tru St Partnership LP ('Tru St') may be deemed the beneficial owner of 1,997,068 shares of common stock. Dr. Caruso is the Chairman Emeritus of Provco Leasing Corporation ('Provco Leasing'). Provco Leasing is the corporate general partner of Tru St. Provco Leasing owns 7,779 shares of common stock directly and is the beneficial owner of 2,004,847 shares of common stock. The Uncommon Individual Foundation is the beneficial owner of 24,382 shares of common stock as of December 31, 2018. Dr. Caruso is the founder and chief executive officer of The Uncommon Individual Foundation. At the quarterly board meeting of The Uncommon Individual Foundation on February 12, 2019, Dr. Caruso stepped down from his positions of The Uncommon Individual Foundation and has been given the honorary title of Chairman Emeritus.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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