Sec Form 4 Filing - GOLDSMITH MARK A @ Revolution Medicines, Inc. - 2020-09-16

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person GOLDSMITH MARK A 2. Issuer Name and Ticker or Trading Symbol Revolution Medicines, Inc. [ RVMD] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) See Remarks (Last) (First) (Middle) C/O REVOLUTION MEDICINES, INC., 700 SAGINAW DRIVE 3. Date of Earliest Transaction (MM/DD/YY) 09/16/2020 (Street) REDWOOD CITY, CA94063 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 09/16/2020 M( 1 ) 8,813 A $ 1.12 8,813 D Common Stock 09/16/2020 S( 1 ) 8,813 D $ 29.043 ( 2 ) 0 D Common Stock 09/17/2020 M( 1 ) 27,363 A $ 1.12 27,363 D Common Stock 09/17/2020 S( 1 ) 4,705 D $ 29.762 ( 3 ) 22,658 D Common Stock 09/17/2020 S( 1 ) 22,658 D $ 31.035 ( 4 ) 0 D Common Stock 09/17/2020 S( 1 ) 11,288 D $ 31.0339 ( 5 ) 114,591 I Trust ( 6 ) Common Stock 09/18/2020 M( 1 ) 1,286 A $ 1.12 1,286 D Common Stock 09/18/2020 M( 1 ) 6,056 A $ 4.09 7,342 D Common Stock 09/18/2020 S( 1 ) 7,142 D $ 31.6555 ( 7 ) 200 D Common Stock 09/18/2020 S( 1 ) 200 D $ 32.185 ( 8 ) 0 D Common Stock 09/18/2020 S( 1 ) 712 D $ 31.0471 ( 9 ) 113,879 I Trust ( 6 ) Common Stock 493,452 I Trust ( 10 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 1.12 09/16/2020 M( 1 ) 8,813 ( 11 ) 04/19/2028 Common Stock 8,813 $ 0 112,165 D Stock Option (Right to Buy) $ 1.12 09/17/2020 M( 1 ) 27,363 ( 11 ) 04/19/2028 Common Stock 27,363 $ 0 84,802 D Stock Option (Right to Buy) $ 1.12 09/18/2020 M( 1 ) 1,286 ( 11 ) 04/19/2028 Common Stock 1,286 $ 0 83,516 D Stock Option (Right to Buy) $ 4.09 09/18/2020 M( 1 ) 6,056 ( 12 ) 03/12/2029 Common Stock 6,056 $ 0 391,908 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other GOLDSMITH MARK A C/O REVOLUTION MEDICINES, INC. 700 SAGINAW DRIVE REDWOOD CITY, CA94063 X See Remarks Signatures /s/ Jack Anders, as attorney-in fact for Mark A. Goldsmith 09/18/2020 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person. ( 2 )The transaction was executed in multiple trades in prices ranging from $29.00 to $29.24, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 3 )The transaction was executed in multiple trades in prices ranging from $29.09 to $29.98, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 4 )The transaction was executed in multiple trades in prices ranging from $31.00 to $31.16, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 5 )The transaction was executed in multiple trades in prices ranging from $31.00 to $31.15, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 6 )Held by the Goldsmith Children 2011 Irrevocable Education Trust. ( 7 )The transaction was executed in multiple trades in prices ranging from $31.03 to $31.94, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 8 )The transaction was executed in multiple trades in prices ranging from $32.13 to $32.24, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 9 )The transaction was executed in multiple trades in prices ranging from $31.01 to $31.21, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. ( 10 )Held by Mark A. Goldsmith and Anne E. Midler 2002 Revocable Living Trust. ( 11 )This option is early exercisable. One forty-eighth (1/48th) of the shares subject to the option will vest on each monthly anniversary measured from March 29, 2018 (the "Vesting Commencement Date"), so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date. ( 12 )This option is early exercisable. One forty-eighth (1/48th) of the shares subject to the option will vest on each monthly anniversary measured from March 13, 2019 (the "Vesting Commencement Date"), so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

Remarks: President and Chief Executive Officer

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* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

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